Naloxone for the Reversal of Opioid Adverse Effects

Marcia L. Buck, PharmD, FCCP


Pediatr Pharm. 2002;8(8) 

In This Article


Since its introduction in 1971, naloxone has served a variety of functions in pediatrics, from reversal of severe respiratory depression in infants born to mothers who received opioids during labor to reduction of adverse effects in children treated with parenteral opioids for pain management.[1] This review will provide guidelines for the administration of naloxone for opioid reversal in children and adults, as well as information on its use in other settings.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.