Jane S. Ricciuti, RPh, MS


September 20, 2002

In This Article

Antiviral Agents

(amprenavir) Capsule and Solution

Manufacturer: GlaxoSmithKline

Drug Approval Classification: Labeling Supplement to Original New Drug Application (Approval Date: 8/02/02)

New Drug Interactions: The labeling for Agenerase has been changed to include:

  • Patients taking Agenerase should be instructed not to use hormonal contraceptives because some birth control pills (those containing ethinyl estradiol/norethindrone) have been found to decrease the concentration of amprenavir. Therefore, patients receiving hormonal contraceptives should be instructed to use alternate contraceptive measures during therapy with amprenavir.

  • Coadministration of Agenerase and methadone can decrease plasma levels of methadone.

Agenerase (amprenavir) Labeling

Agenerase (amprenavir)


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