Conference Report From the 10th World Congress on the Menopause

Professor Lorraine Dennerstein, AO MBBS, PHD, DPM, FRANZCP

Disclosures

July 03, 2002

In This Article

Predicting the Onset of Menopause

Dr. John Taffe of the Swinburne University of Technology, Melbourne,[12] also used the Melbourne data in his presentation during "The Aging Endocrinium" session of the conference. Taffe used data from daily menstrual calendars kept by women for up to 9 years to describe changes in menstrual cycles leading up to the FMP .[13,14] Taffe and Dennerstein[13] compared sequences of at least 10 unbroken cycles from women collected before the early menopausal transition phase with those 10 cycles leading up to the FMP. Mean cycle lengths were unchanged in the earlier sequences. Early sequences were used to classify menstrual regularity. Sequences in the early cycles seldom varied outside the 21- to 35-day range. Characteristic of approaching FMP was an increasing cycle irregularity and length, rising above 35 days during the last 10 cycles. Once the difference between longest and shortest cycles became ≥ 42 days, the FMP could be expected within 1 year for those with FSH > 20 IU/L and who perceived themselves to be in the menopausal transition.[14] Thus, knowing a few variables (age, menstrual onset calendar, FSH, woman's perception of whether her menopausal transition has begun) allows a clinician to advise a woman that she is within a year of her final menstruation.

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