Feline Host Range of Canine parvovirus: Recent Emergence of New Antigenic Types in Cats

Yasuhiro Ikeda, Kazuya Nakamura, Takayuki Miyazawa, Yukinobu Tohya, Eiji Takahashi,Masami Mochizuki

Disclosures

Emerging Infectious Diseases. 2002;8(4) 

In This Article

Feline Host Range of CPV in the Wild

In late 1980s, CPV was first recognized in cats in a natural setting [30]. Mochizuki et al. [30] examined eight feline isolates collected during 1987 to 1991 in Japan and demonstrated that three were antigenically and genetically identical to CPV-2a viruses. The first isolation of CPV-2a-type virus from a cat was in 1987 [30]. All three CPV-2a-type viruses were isolated from the feces of clinically healthy cats, while the isolates from cats with typical feline panleukopenia were all conventional FPLV-type. Subsequently, CPV-2a and CPV-2b viruses were recognized in cats in the USA (2 of 20 isolates) and Germany (3 of 36 isolates) [33].

Recently, Ikeda et al. [11] examined 18 isolates from unvaccinated cat populations and demonstrated that 15 of the isolates could be classified as CPV-2a- or 2b-related viruses [11]. Since carnivore parvoviruses are likely to spread freely and rapidly in the environment when few cats and dogs are vaccinated against FPLV or CPV, CPV-2a/2b-type viruses seem to have more advantages over conventional FPLV in cats under natural conditions. It is therefore possible that CPV-2a/2b-type viruses will replace FPLV-type viruses as the dominant infectious agents in domestic cats even in developed countries, where FPLV vaccines are commonly used.

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