Feline Host Range of Canine parvovirus: Recent Emergence of New Antigenic Types in Cats

Yasuhiro Ikeda, Kazuya Nakamura, Takayuki Miyazawa, Yukinobu Tohya, Eiji Takahashi,Masami Mochizuki

Disclosures

Emerging Infectious Diseases. 2002;8(4) 

In This Article

Persistent Infection of CPV in Cats

Animals that recover from feline parvovirus infection retain high specific neutralization antibodies and show no virus shedding. Although isolation of FPLV from apparently healthy cats has been reported, feline parvoviruses are generally believed to be completely eliminated from recovered animals.

As mentioned, CPV-type viruses have been isolated from the fecal samples of apparently healthy cats [30]. Moreover, many CPV-type viruses were isolated from the peripheral blood mononuclear cells (PBMC) of cats with high specific neutralizing antibodies [11,35,39], suggesting that CPV could persistently infect cats irrespective of the presence of the neutralizing antibodies. Although precise mechanisms of the persistent infection of CPV remain to be determined, PBMC probably play a role as a reservoir for the viruses. If one assumes that CPV actually infects cats persistently, examination will be needed to determine whether sporadic shedding of the virus occurs in recovered cats.

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