Abstract and Introduction
Since the emergence of Canine parvovirus (CPV-2) in the late 1970s, CPV-2 has evolved consecutively new antigenic types, CPV-2a and 2b. Although CPV-2 did not have a feline host range, CPV-2a and 2b appear to have gained the ability to replicate in cats. Recent investigations demonstrate the prevalence of CPV-2a and 2b infection in a wide range of cat populations. We illustrate the pathogenic potential of CPV in cats and assess the risk caused by CPV variants.
Human health and animal welfare continue to be challenged by rapidly evolving pathogens. Although many details about specific host-parasite systems have been reported, our understanding of host range alteration and the evolution of virulence remains rudimentary. We reviewed the evolution of carnivore parvoviruses with particular reference to Canine parvovirus (CPV) infection in cats. These parvoviruses' molecular and phenotypic evolutionary pattern provides an exemplary system to study pathogen-host relationships and the evolution of virulence, both essential factors for understanding newly emerging infectious diseases.
Emerging Infectious Diseases. 2002;8(4) © 2002 Centers for Disease Control and Prevention (CDC)
Cite this: Feline Host Range of Canine parvovirus: Recent Emergence of New Antigenic Types in Cats - Medscape - Apr 01, 2002.