Sumatriptan: Pharmacological Basis and Clinical Results

Carl G. H. Dahlöf


Curr Med Res Opin. 2001;17(1s) 

In This Article


The introduction of sumatriptan a decade ago changed the face of migraine management. For the first time, therapy could be targeted at the hypothesized physiological source of migraine pain with resultant improvement over non-selective pharmacotherapies in efficacy. The introduction of sumatriptan stimulated research into the epidemiology and public health impact of migraine, encouraged efforts to further delineate migraine pathophysiology, and inspired the development of a generation of sumatriptan-like compounds - the triptans. This article reviews early and recent data on sumatriptan and considers the place of sumatriptan in migraine therapy a decade after its introduction.


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