Kaposi's Sarcoma

Tania J. Phillips, MD, FRCPC

Disclosures

Wounds. 2001;13(6) 

In This Article

Case Study

A 94-year-old Caucasian man presented with an ulcer on the medial side of his left foot. His past medical history was significant for an 18-year history of Kaposi's sarcoma on his hands and feet. Seven months prior to presentation, the patient developed an ulcer on the plantar surface of his left foot with cellulitis. The infection cleared with oral antibiotics and the ulcer healed approximately two months prior to his presentation, but recurred approximately four weeks prior to the visit. The ulcer was painful. He denied anesthesia, paresthesia, claudication, or previous deep vein thrombosis.

His past medical history included arthritis, hypertension, hernia, prostate cancer, depression, and cutaneous basal and squamous cell carcinomas.

He had been treating the wound with alternating mupirocin and silver sulfadiazine creams and a dry gauze bandage. His other medications include doxorubicin for his Kaposi's sarcoma, fosinopril, digoxin, and multivitamins. He was previously treated with paclitaxel. His son noticed that the ulcer increased in size while on paclitaxel, but after starting doxorubicin for his Kaposi, the ulceration had improved.

Physical examination revealed a pleasant elderly gentleman with extensive photodamage and multiple seborrheic keratoses and actinic keratoses on the upper extremities, chest, and back. Peripheral pulses of the lower extremities were normal. The ankle brachial pressure index was 1.0. There were numerous superficial, clean appearing ulcers over the medial aspect of his left foot, surrounded by hyperkeratotic tissue. There was background violaceous discoloration of the foot (Figure 1).

There were numerous superficial, clean appearing ulcers over the medial aspect of his left foot, surrounded by hyperkeratotic tissue. There was background violaceous discoloration of the foot.

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