Prussian Blue for Treatment of Radiocesium Poisoning

Dennis F. Thompson, Pharm.D., FASHP, FCCP, and Chelsea O. Church, Pharm.D.

Disclosures

Pharmacotherapy. 2001;21(11) 

In This Article

Conclusion

Prussian blue is a crystal lattice that exchanges potassium for cesium at the surface of the crystal. When given orally, it binds cesium secreted in the gut before it can be reabsorbed. In humans, the agent can reduce cesium's half-life by approximately 43% and reduce total body burdens. It is well tolerated at a dosage of 3 g/day with appropriate monitoring of serum potassium levels and observing for signs of constipation.

Comments

3090D553-9492-4563-8681-AD288FA52ACE

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