Population Pharmacokinetics of Intravenous and Intramuscular Streptomycin in Patients with Tuberculosis

Min Zhu, Ph.D., William J. Burman, M.D., George S. Jaresko, Pharm.D., Shaun E. Berning, Pharm.D., Roger W. Jelliffe, M.D.,and Charles A. Peloquin, Pharm.D.


Pharmacotherapy. 2001;21(9) 

In This Article


The NPEM models established in this study can provide accurate kinetic estimates even with a sparse sampling strategy. Parameter estimates can be incorporated into Bayesian pharmacokinetic models for use in therapeutic drug monitoring for patients with tuberculosis.


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