Respiratory Viral Infections and Asthma: Is There a Link?

Erwin W. Gelfand, MD

In This Article

Prospects for Prevention and Treatment: Vaccines

A number of new approaches toward developing an RSV vaccine have shown promise despite many earlier failures.[6] Two major problems have slowed the development of effective RSV vaccines. The first issue is that prior immunity can enhance the severity of naturally occurring disease. Second, natural infection does not result in specific protection against reinfection.

The new vaccines include a purified fusion protein vaccine, a reverse engineered live attenuated vaccine, and naked DNA vaccination. A humanized monoclonal antibody to RSV has been shown to be effective in preventing lower RTI in high-risk children with bronchopulmonary dysplasia.[13]


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