Viral respiratory infections have been estimated to account for more than 80% of acute exacerbations of asthma in children and at least 30% to 40% of exacerbations in adults with asthma. The most significant asthma-associated viruses include respiratory syncytial virus (RSV), rhinovirus, and parainfluenza. This article will review the association of respiratory viral infections and asthma, bronchial inflammation and airway hyperresponsiveness associated with viral infections, viral-induced effectors of the inflammatory response, the role of noninflammatory mechanisms in virus-induced wheezing, the persistence of infection, the interactions between viral respiratory tract infection (RTI) and allergic sensitization, and current developments in vaccines for viral infections.
© 2000 Medscape
Cite this: Respiratory Viral Infections and Asthma: Is There a Link? - Medscape - Jul 13, 2000.