Cystic Fibrosis and Nasal Polyposis

Ford D. Albritton IV, MD, and Todd T. Kingdom, MD, Emory University, Atlanta, Ga.

In This Article


Sinonasal polyps are characterized by smooth, pale, almost translucent mucosa on a pedunculated or sessile base. They can occur anywhere in the sinus cavity, often along the middle meatus. Polyps are frequently multiple and bilateral, and their symptoms relate to their obstructive nature and include nasal stuffiness, mouth breathing, facial pain/pressure, anosmia, and even rhinorrhea.[1]

All that resembles a polyp is not a polyp. The differential diagnosis includes other nasal masses, such as gliomas and encephaloceles, as well as normal variants of nasal anatomy. Workup should include a thorough history and rhinoscopic exam. Sinonasal polyposis may be seen in a myriad of clinical situations including asthma, allergic rhinitis, immotile cilia syndrome, allergic fungal sinusitis, chronic sinusitis, and CF. Most commonly they are associated with allergic rhinitis and CF.[2,3]


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