Robert Kennedy, Kelley Suttenfield

Disclosures
In This Article

Risk Factors

Biological risk factors that contribute to the development of PPD include:

  1. A history of depression in previous pregnancies or postpartum period. Women with previous pregnancy-related depressive episodes are at a 50% to 62% increased risk of recurrent episodes with subsequent pregnancies.[5]

  2. A previous history of depression. Up to 30% of women who have experienced a major depressive episode prior to conception will develop PPD.[15]

  3. A history of depression in blood relatives. The risk of depression is higher with a positive family history and is greatest if a relative experienced a PPD.[7,8]

  4. There are several other psychosocial risk factors that may contribute to a heightened risk of depression in both pregnancy and the postpartum period. These include poor social support, adverse life events, marital instability, and ambivalence towards the pregnancy.[7,8,11,15]

In an often-cited study by Kendall

[11]

concerning affective disorder in the puerperium, a sharp increase in psychiatric admissions during the first 3 months after delivery was demonstrated. Women at highest risk were those with a history of a mood disorder or those who experienced depression during pregnancy.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....