Treatment of Perianal Crohn's Disease: State of the Art

David A. Schwartz, MD, and William J. Sandborn, MD, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minn.


May 16, 2000

In This Article


Perianal fistulas are a frequent manifestation of Crohn's disease and can result in significant morbidity, including scarring, fecal incontinence, and the need for surgery. Before 1970, therapeutic options were limited to antibiotics or surgery. During the past 30 years, the options for the medical treatment of fistulizing Crohn's disease have changed dramatically. This article reviews these therapeutic options and their implications for disease management.


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