Alternatives to Phenylpropanolamine

W. Steven Pray, Ph.D., R.Ph., Professor of Nonprescription Products and Devices, School of Pharmacy, Southwestern Oklahoma State University, Weatherford, OK

US Pharmacist. 2001;26(1) 

In This Article

Introduction

Use of the ingredient phenylpropanolamine (PPA) is an issue that has been fraught with controversy for several decades. Many who used PPA escaped without adverse events; however, its side-effect profile was too high for general consumer safety. The sheer variety of adverse reactions reported in the medical literature was equally disturbing to concerned medical professionals.

Nonetheless, nonprescription product manufacturers continued to assert that the substance was safe and effective for both nasal congestion and weight loss. Many of the best-selling products contained the ingredient, and it was widely marketed to the lay public, despite preliminary data suggesting that it was responsible for serious patient harm.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....