Lysine for Management of Herpes Labialis

Frankie A. Tomblin, Jr., Pharm.D. and Kristy H. Lucas, Pharm.D.

Disclosures

Am J Health Syst Pharm. 2001;58(4) 

In This Article

Contraindications

Lysine supplementation is contraindicated in patients with renal disease or hepatic impairment.[2] Patients with renal or hepatic disease may not be able to eliminate the large amounts of nitrogen produced upon breakdown of the supplemented amino acid. No data support the use of lysine in children or in pregnant or breast-feeding women. Interactions. Studies indicate that concomitant use of lysine and calcium can increase the absorption and decrease the elimination of calcium.[23] Large doses of lysine have been reported to increase the toxicity of aminoglycosides by an unknown mechanism.[2]

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