DHEA: Dehydroepiandrosterone


Am J Health Syst Pharm. 2000;57(22) 

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Drug Interactions

Calcium-channel blockers and metformin increase levels of endogenous DHEAS, whereas corticosteroids and insulin significantly decrease them.[3] Supraphysiological dosages of DHEA can increase serum triazolam levels because of an inhibition of metabolism.[8] Theoretically, aromatase inhibitors, such as chrysin (5.7-dihydroxyflavone), an extract from the plant Passiflora coerula, can increase levels of androgens, including DHEA and DHEAS, in both men and women. Kroboth et al.[3] published an excellent review of the effects of disease, diet, exercise, and medications on endogenous DHEA and DHEAS levels.


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