Angiotensin II-Receptor Antagonists: An Overview

Raquel Dina and Mahtab Jafari


Am J Health Syst Pharm. 2000;57(13) 

In This Article

Formulary Recommendations

Angiotensin-II-receptor antagonists seem to be as effective as ACE inhibitors for treating hypertension and can be initiated in patients who are unable to tolerate an ACE inhibitor. All available AT-II-receptor antagonists seem to be equally effective in reducing both systolic and diastolic blood pressure, and they are comparable in cost.

Losartan is unique among AT-II-receptor antagonists in that it has the ability to increase uric acid excretion, which in turn lowers plasma uric acid levels 22 ; however, the clinical importance of this characteristic has yet to be determined.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.