Drug-Induced Nail Disorders: Prevention Is Best

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Drug-Induced Pigmentation Slow to Disperse

Excretion or deposition of the drug in the nail can lead to yellow discolouration with tetracycline[11] or gold salts,[12] dark-brown discolouration with clofazimine,[13] blue-grey pigmentation with minocycline[14] and blue, brown or grey colouration with antimalarial agents.[15] The skin, sclerae and mucous membranes may also be affected with minocycline and antimalarials. Nail pigmentation may persist unchanged for years after drug interruption, although it may decrease in intensity.


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