Vasculitis and Related Disorders

  • Ask the Experts - Unusual Presentation of Raynaud's Phenomenon A 40-year-old male smoker presents with a type of Raynaud's phenomenon that affects the long finger of the left hand only. Discoloration and severe pain of the finger develops whenever it is exposed to cold weather. He works in construction outdoors and is concerned that he will be unable to work during the winter.
  • Ask the Experts - Cyclophosphamide for Wegener's Granulomatosis A patient with a severe form of Wegener's granulomatosis is receiving high doses of cyclophosphamide.  Monitoring leukocyte count may prevent possible toxicity.  Does it also give indirect evidence for the efficacy of the treatment? Is there an optimum level of white blood cell (WBC) count for this patient? Is it acceptable for this patient to receive different doses of cyclophosphamide
  • Ask the Experts - Complex Case with Evanescent Constellation of Symptoms These findings are not typical of palindromic rheumatism, scleroderma or calcinosis cutis, Raynaud's phenomenon, esophageal dysfunction hypermotility, sclerodactyly, or telangectasia (CREST) syndrome.
  • Ask the Experts - Prostatitis, Arthritis, Low Back Pain, and Other... The patient has now failed to respond adequately to rofecoxib, indomethacin, ibuprofen, and other nonsteroidal anti-inflammatory drugs (NSAIDs) at maximal appropriate dosing. He may be allergic to sulfonamides and therefore is not a candidate for azulfidine. Is this man's syndrome driven by continuing prostatis, and should antibiotics be continued? Is serum Mycoplasma by polymerase chain
  • Ask the Experts - APS and Livedo Reticularis I recently saw a patient with livedo reticularis. I recall that this can be associated with antiphospholipid antibody syndrome (APS). Is there anything else that I should be worried about or look for? The patient's medical history includes asthma, chronic sinusitis, and seasonal allergies.
  • Ask the Experts - Upper GI Bleeding in a Thrombocytopenic Patient How would you approach an 82-year-old man with lymphopenia, thrombocytopenia, a highly positive antinuclear antibody (ANA) of 1:2560, and duodenal bleed?
  • Ask the Experts - Diagnosing Antiphospholipid Syndrome Can antiphospholipid syndrome (APS) be diagnosed without a documented thrombotic event or the recently proposed pregnancy morbidity criteria? I ask this in view of the consensus statement on preliminary classification criteria for definite APS.
  • Ask the Experts - Henoch-Schönlein Purpura and Microaneurysms Can patients with Henoch-Schonlein purpura have microaneurysms?
  • Ask the Experts - Parsonage-Turner Syndrome What is Parsonage-Turner syndrome?