Lung Cancer

 
 

Lung Cancer

  • Therapy Options for Limited-Stage, Small-Cell Lung Cancer? A 58-year-old woman with SCLC received 3 cycles of cisplatin-etoposide plus 25 doses of concurrent 45 Gy thoracic RT. Follow-up CT demonstrated a good response. What would you recommend at this point?
  • Follow-up Therapy for Locally Advanced Pancoast Tumor? A right-sided Pancoast tumor involving the upper lobe with rib destruction in a 54-year-old man remained unchanged after 4 cycles of carboplatin and paclitaxel and irradiation. What you would suggest?
  • Therapeutic Options for an Elderly Woman With Metastatic NSCLC? PET scan of a 74-year-old woman who smokes revealed a tumor in the right lower lobe and 3 tumors near the adrenals. Biopsy confirmed squamous cell carcinoma. How would you proceed?
  • Treatment Options for Bronchioloalveolar Carcinoma? A 55-year-old female former smoker was diagnosed with bronchioloalveolar cell carcinoma, possibly involving both lungs. No other metastases were noted, and her PS is 1. What would you suggest?
  • Treating Limited-stage SCLC? Two years after chest x-ray and ultrasound showed a small hilar mass in a 48-year-old heavy smoker, repeat scans showed that the mass was now 2.5 cm, and biopsy demonstrated SCLC. What would you do?
  • Therapy Options for Primary Pulmonary NHL? A 69-year-old woman with incidental findings of a follicular lymphoma of the mid-lobe of the right lung showed minimal evidence of follicular (small-cell) lymphoma. What would you recommend?
  • Asymptomatic Locally Advanced Unresectable NSCLC? A 61-year-old man with NSCLC stage IIIB was treated with radiotherapy and chemotherapy 1 year ago. He is now disease-free on MRI and CT, but PET shows a single node at the aortic window.
  • Follow-up Therapy for a Stage IIIB Pulmonary Blastoma? A stage IIIB pulmonary blastoma was diagnosed in a 42-year-old man with a 30-pack-year history of smoking. What would you recommend after daily radiation and weekly chemotherapy?
  • Treatment Options for Pancoast Tumor? A 55-year-old woman was diagnosed with stage IIIB T4N0M0 squamous cell Pancoast tumor involving the adjacent vertebrae (T1-T3) and extending into the neural canal. What would you do?
  • Metastatic NSCLC Causing Obstructive Jaundice? A 42-year-old man with obstructive jaundice showed a left-sided mass on CT; local nodes were positive for disease. Could the obstruction be caused by metastatic deposits in the periampullary region?
  • Postoperative Therapy for Stage IA NSCLC? CT scan of a 56-year-old man showed a 3-cm mass in the LLL. Mediastinoscopy was negative and a 2.8-cm adenocarcinoma was removed. All nodes were negative. Is there any role for postoperative therapy?
  • Treating Locally Advanced NSCLC With Possible Nodal Involvement? Chest x-ray of a 63-year-old woman showed a 3.4-cm mass in the periphery of the RUL. CT scan showed no disease in the mediastinum, but PET scan showed nodal involvement. What would you suggest?
  • Therapy for Asymptomatic Malignant Pleural Mesothelioma? Thoracoscopic pathology of a 66-year-old male revealed epithelial mesothelioma with involvement of the lung and ipsilateral hilar lymph nodes. Resection is not possible. What would you recommend?
  • Treating Small-Cell Lung Cancer Metastatic to the Brain? A 58-year-old man with metastatic SCLC demonstrated complete remission after cisplatin/etoposide, but declined PCI. CT now shows multiple cerebral and cerebellar metastases. What would you suggest?
  • Third-line Therapy for NSCLC? A 46-year-old man with widespread metastatic NSCLC failed therapy with cisplatin/etoposide/ifosfamide and paclitaxel/carboplatin. What would you recommend as third-line therapy?
  • Treatment for Radiation Pneumonitis Prednisone 10 mg alleviates the patient's cough, but the side effects are prohibitive -- any other suggestions?
  • Treating Lung Cancer Metastatic to the Brain? A 64-year-old woman presented with an adenocarcinoma of the lung and a metastatic lesion in the left frontal lobe of her brain. What would you recommend: radiotherapy, chemotherapy, and/or surgery?
  • Treating Early-Stage NSCLC? A well-differentiated peripheral adenocarcinoma was removed by lobectomy. The surgical field was clean, and no regional or mediastinal lymph nodes were involved. What would you recommend as follow-up?
  • Treating Super-Limited Small-Cell Lung Cancer? A 67-year-old male smoker presented with pneumonia and was found to have a 5-cm peripheral RUL mass.
  • Brochoalveolar NSCLC With a History of NHL? An 80-year-old female recently underwent a right lower lobe lobectomy for a 12-mm diameter primary lung carcinoma.