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Genomics in Practice at the 2013 European Cancer Congress
Dr. Maurie Markman looks at a few presentations from the 2013 European Cancer Congress that highlight the practical role of genetic testing in the management of cancer.
Experts And Viewpoints, October 31, 2013
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A Brief Look: Cancer Genomic Medicine at ASCO® 2013
Dr. Maurie Markman takes a brief look at a few presentations from ASCO 2013 that highlight the evolving role of genomics in the management of cancer.
Experts And Viewpoints, August 21, 2013
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Using the Gut Microbiome Genome to Predict Type 2 Diabetes
Dr. Ali Torkamani reviews a recent study that examined changes in the gut microbiome genome in relation to changes in glucose tolerance and type 2 diabetes.
Experts And Viewpoints, July 31, 2013
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Elevated BMI vs Severe Obesity: Different Genetic Diseases?
Dr. Ali Torkamani looks at 2 studies questioning whether genetics can be used to define severe obesity as a separate disease.
Experts And Viewpoints, June 11, 2013
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A Window Into the Future of Cancer Monitoring
Dr. Maurie Markman reviews a recent paper that describes the use of circulating tumor DNA as a new approach to monitor response to antineoplastic therapy.
Experts And Viewpoints, April 24, 2013
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Targeted Therapy for Papillary RCC: An Uncommon Approach
Dr. Maurie Markman considers a new therapy that targets an uncommon mutation in the uncommon papillary subtype of renal cell carcinoma.
Experts And Viewpoints, March 06, 2013
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Trastuzumab Resistance: Can Genetics Lead Us to New Options?
Dr. Maurie Markman looks at how research into genetic changes in trastuzumab-resistant breast cancers might open the door to new treatment options.
Experts And Viewpoints, January 23, 2013
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Genetic Underpinnings of IBD: Immunity, Infection, and More
Dr. Dermot McGovern reviews a recent meta-analysis of genetic studies of inflammatory bowel disease and its links to immune diseases, mycobacterial infections, and more.
Experts And Viewpoints, January 10, 2013
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Progress in Cancer Genomic Medicine: A Year in Review, 2012
Dr. Maurie Markman looks back at key research studies from 2012 and discusses how they affect our understanding of the role of cancer genomics in clinical practice.
Experts And Viewpoints, December 14, 2012
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Should We Test Lp(a) to Predict Risk for Atherosclerosis?
Dr Deepak Voora considers the clinical implications of recent data demonstrating an association between lipoprotein(a) levels and atherosclerosis.
Experts And Viewpoints, December 12, 2012
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Targeted Therapies on the Horizon for Squamous Lung Cancers
Dr. Maurie Markman considers the clinical and therapeutic consequences of the first-ever genomic characterization of squamous lung cancers.
Experts And Viewpoints, November 20, 2012
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Genetic Tracking of an Infection Outbreak: The Future Is Now
Dr. Christopher Woods looks at the use of whole genome sequencing to track an infection outbreak in a research hospital and considers when this technology might be available in clinical practice.
Experts And Viewpoints, November 05, 2012
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Genetic Biomarker for Taxane-Induced Neuropathy
Dr. Maurie Markman looks at a recent study that identified a genetic marker significantly associated with taxane-induced peripheral neuropathy.
Experts And Viewpoints, November 01, 2012
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Squaring Genetic vs Clinical Findings in Familial Polyposis
What should we do if the genetics and clinical presentation don't align in patients with familial adenomatous polyposis? Dr. Ora Gordon and genetic counselor Tali Geva weigh in.
Experts And Viewpoints, October 04, 2012
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EGFR Mutation Status and TKI Use in NSCLC: The Final Word
Should EGFR TKIs be considered in patients with advanced NSCLC if mutation status is unknown? Dr. Maurie Markman reviews a study that offers the final word.
Experts And Viewpoints, September 12, 2012
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Preventing Head and Neck Tumors the Genetic Way
Chemoprevention of head and neck cancers with retinoic acid showed mixed trial results. But as Dr. Maurie Markman explains, genetics might help in predicting responders.
Experts And Viewpoints, August 28, 2012
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Type 2 Diabetes in Lean Individuals: A Different Disease?
Type 2 diabetes is associated with obesity, but lean individuals develop the disease as well. Dr. Ali Torkamani reviews a recent paper implicating unique genetic variants in lean diabetics.
Experts And Viewpoints, August 02, 2012
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CLL Genomics: Converting a Prognostic Factor Into a Target
TP53 deletion is known to be an adverse prognostic factor in patients with chronic lymphocytic leukemia. Dr. Maurie Markman looks at how it can be used as a target for therapy.
Experts And Viewpoints, July 26, 2012
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Gene Therapy for HIV
Drs. Scott Kitchen and Jerome Zack discuss how genetically modifying peripheral T cells and other gene therapy approaches might prove useful in the clinic.
Experts And Viewpoints, June 28, 2012
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Olaparib in Ovarian Cancer: Parsing the Data
A phase 2 trial of olaparib showed improvements in PFS but not OS in patients with ovarian cancer. Dr. Maurie Markman explains why.
Experts And Viewpoints, June 25, 2012
