Review of Therapeutics

 
 
  • Pharmacologic Treatment of Type 2 Diabetic Dyslipidemia Diabetic patients tend to have a higher concentration of small dense LDL particles, which are associated with a higher CHD risk.
  • Atazanavir for Treatment of HIV Infection Atazanavir is the first once-daily protease inhibitor for the treatment of HIV-1 infections and should be used only in combination therapy.
  • Intradialytic Parenteral Nutrition Well-designed, prospective studies are required to confirm these effects.
  • Drug Eluting Stents Despite the introduction of intracoronary stents and the addition of systemic pharmacotherapy, restenosis still affects a significant number of patients.
  • Bone Disorders Associated With HIV: Pathogenesis & Management Osteopenia, osteoporosis and osteonecrosis have been reported in HIV-infected patients
  • Immunosuppressive Strategies in Renal Transplantation
  • Paradoxical Reactions to Benzodiazepines Benzodiazepines are used primarily in the treatment of generalized anxiety and panic disorders, as sedative hypnotics, muscle relaxants, and anticonvulsants.
  • Atomoxetine, a Novel Treatment for ADHD Attention-deficit-hyperactivity disorder (ADHD) is the most frequently diagnosed neurobehavioral childhood disorder.
  • Clopidogrel: From Literature and Guidelines to Practice Acute coronary syndromes (ACS) has become a familiar, yet broad, classification of conditions that include unstable angina and non-ST-segment elevation myocardial infarction.
  • Magnesium for Atrial Tachyarrhythmias Magnesium is inexpensive and has a favorable tolerability profile. Current agents used for treatment and prevention often have limited efficacy and can have an unfavorable adverse-effect profile.
  • Cross-Allergenicity of Sulfonamide Antibiotics & Other Drugs This article addresses the mechanisms, stereochemistry and adverse reactions to sulfonamide antibiotics. Concerns about cross-allergenicity persist and can complicate patients' drug therapy.
  • Food: An Unrecognized Source of Loop Diuretic Resistance Loop diuretics are a common class of drug used in the treatment of chronic conditions such as chronic heart failure (CHF) and renal failure.
  • Delaying the Onset of Type 2 Diabetes Mellitus in Patients Type 2 diabetes mellitus is a chronic disease that is increasing at epidemic rates and is associated with significant microvascular (e.g., retinopathy) and macrovascular (e.g., cardiovascular disease) complications.
  • Enfuvirtide, a New Fusion Inhibitor for Therapy of HIV Infection The morbidity and mortality associated with human immunodeficiency virus (HIV) infection have decreased dramatically since the introduction of combination therapy of nucleoside reverse transcriptase inhibitors (NRTI) with either a protease inhibitor and/or a nonnucleoside reverse transcriptase inhibitor (NNRTI).
  • Aripiprazole, a Novel Atypical Antipsychotic Drug Schizophrenia is a disabling and devastating illness characterized by a constellation of psychotic, mood, and cognitive symptoms.
  • Managing Anemia in the Critically Ill Patient Anemia of critical illness is defined as anemia in the critically ill patient that cannot be explained by other causes and that is charac-terized by an inadequate response of endogenous erythropoietin in relation to the degree of hemoglobin deficiency present.
  • Daptomycin The past 10 years have seen a nearly 25% increase in resistance among gram-positive pathogens in the United States, most notably, staphylococci, enterococci, and streptococci.
  • Investigational Antimicrobials for Multidrug-Resistant Bacteria The emergence of and growth in antimicrobial resistance among gram-positive microorganisms complicate the treatment of infections due to such pathogens.
  • Epidemiology and Clinical Management of Inhaled Nitrate Abuse Drugs such as 3,4-methylenedioxy-meth-amphetamine (MDMA, Ecstasy), γ-hydroxybutyric acid (GHB), methamphetamine, and ketamine are popular substances of abuse in social settings such as bars and dance clubs.
  • Nonhormonal Alternatives for the Treatment of Hot Flashes Hot flashes affect approximately 75% of postmenopausal women and are one of the most distressing symptoms women experience as they enter menopause.