Review of Therapeutics

Pharmacokinetics of Intravenous Immunoglobulin Despite the large number of studies characterizing IGIV pharmacokinetics, major gaps remain in the literature, including a lack of information on IGIV clearance.
Journal Article, June 01, 2006
An Antifolate Therapeutic Alternative for Cancer Chemotherapy This newly approved agent should be used as a standard of care for unresectable malignant pleural mesothelioma and recurrent malignant non-small cell lung cancer.
Journal Article, May 01, 2006
Update on Prostate Cancer Chemoprevention The prevalence of prostate cancer and its long lead time to clinically significant disease make it ideal for pharmacological or nutritional prevention strategies.
Journal Article, March 01, 2006
Rosiglitazone and Pioglitazone on Cardiovascular Risk Clinical data supporting the use of these agents to improve heart disease risk factors is intriguing, but caution must be used when translating them for clinical practice.
Journal Article, February 01, 2006
Pharmacotherapy for Idiopathic Pulmonary Arterial Hypertension This review covers the latest drug regimens for treating IPAH, including epoprostenol, treprostinil, iloprost, bosentan, and sildenafil, as well as investigational agents.
Journal Article, January 01, 2006
Combating Influenza With Antiviral Therapy Antiviral therapy is not a substitute for the flu vaccine, but it can be used to treat and possibly prevent influenza in the pediatric population.
Journal Article, January 01, 2006
Perioperative Antiinflammatory and Immunomodulating Therapy Patients who take NSAIDs to manage chronic conditions may have delayed healing of surgical wounds. Clinicians must weigh the risks and benefits to determine when to discontinue and resume therapy.
Journal Article, November 01, 2005
Multidrug-Resistant Pseudomonas Aeruginosa The increasing frequency of these resistant strains requires careful selection of the best antimicrobial therapies.
Journal Article, October 01, 2005
Education and Treatment Strategies at a Hepatitis C Virus Clinic Strategies used by clinical pharmacists at a California HCV clinic can facilitate a successful treatment outcome for patients while enabling them to maintain a reasonable quality of life.
Journal Article, September 01, 2005
Protective Effects of Angiotensin II Interruption Angiotensin II receptor blockers may represent a novel class of antiinflammatory drugs that have indications far beyond cardiovascular diseases.
Journal Article, September 01, 2005
Ketamine for Conscious Sedation in Pediatric Emergency Care A literature review shows this drug is both effective and highly rated by both physicians and patients.
Journal Article, August 01, 2005
Aspirin Resistance: An Evaluation About 26 million Americans take aspirin daily to prevent heart attacks, but how many are actually receiving a benefit?
Journal Article, July 01, 2005
Hyperglycemia and Infection in Critically Ill Patients Intensive insulin therapy to maintain tight blood sugar levels also helps lower infection risks in critically ill patients.
Journal Article, July 01, 2005
Cidofovir for Treatment of Recurrent Respiratory Papillomatosis Case studies describe promising results with the anti-viral drug cidovir in treating this otherwise intractable infection.
Journal Article, July 01, 2005
Rosuvastatin for the Treatment of Hypercholesterolemia A new statin could be a first-line option for patients needing to lower their LDL levels by 50% or more.
Journal Article, July 01, 2005
Alfa for the Treatment of Combination Therapy-Induced Anemia Exogenous epoetin alfa therapy shows promise in patients who develop anemia due to antiviral therapy for hepatitis C, but more data are needed to optimize treatment.
Journal Article, June 01, 2005
Antiinflammatory Therapies for Cystic Fibrosis Review the use of anti-inflammatory medications for cystic fibrosis.
Journal Article, April 01, 2005
Antibiotic Lock Technique: Review of the Literature This controversial technique is used for sterilizing the lumen of central venous catheters and involves instilling high concentrations of antibiotics with or without heparin.
Journal Article, February 01, 2005
Statins and Osteoporosis: A Clinical Review Statins have shown positive effects on bone mineralization. Clinical data on surrogate markers and fracture rates are conflicting. Use of statins in treating osteoporosis requires further study.
Journal Article, February 01, 2005
Community Associated Methicillin-Resistant Staphylococcus Aureus Identification of the potential risk factors for CA-MRSA acquisition, and characterization of the properties of these strains are necessary to provide effective therapeutic guidelines.
Journal Article, January 01, 2005

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