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Depression, Distress, and Stroke
Major depression increases the risk for heart disease and psychological distress is associated with increased morbidity and mortality, but does either condition affect risk for stroke?
Journal Article, June 20, 2008
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Emotional Health = Heart Health
Does emotional vitality--a sense of positive energy, an ability to regulate behavior and emotions, and a feeling of engagement in life--decrease the risk for developing coronary heart disease?
Journal Article, January 28, 2008
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Steroids in Septic Shock: Not Looking Good
Septic shock therapy guidelines recommend steroids largely based on one well-conducted study's results. In a multicenter randomized, controlled double-blind study, how did steroids compare to placebo?
Journal Article, January 09, 2008
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Mania in Teens: How to Treat?
Adolescent mania is challenging to treat and is associated with poor prognosis. How do response and remission rates of olanzapine compare with placebo in treating mixed and manic episodes in teens?
Journal Article, November 19, 2007
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A New Treatment Approach for Bipolar Depression
Bipolar depression is incredibly difficult to treat. Might add-on modafinil therapy help treat bipolar depression in patients with inadequate response to mood stabilizers?
Journal Article, September 24, 2007
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Combined Therapy for Adolescents With Depression?
Depressed children have been shown to improve more with SSRI plus cognitive-behavioral therapy than with SSRI alone. This study further tested efficacy of combination therapy versus medication alone.
Journal Article, July 20, 2007
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How Should Bulimia Nervosa in Adolescents Be Treated?
In adolescents with bulimia nervosa, is family therapy or therapist-supported, self-guided, manual-based, cognitive-behavioral therapy more effective in treating this eating disorder?
Journal Article, May 07, 2007
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Psychodynamic Psychotherapy for Panic Disorder?
First-ever report of efficacy for panic-focused psychodynamic therapy. Studies needed to test whether this benefit lasts long-term and compares directly with CBT and medications.
Journal Article, March 01, 2007
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The Depression of a Broken Heart
Like anger, does depression trigger acute coronary syndrome? Via what mechanism? Will treating depression change this pattern?
Journal Article, January 23, 2007
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Neurofeedback for ADHD
Determining nonpharmacologic ways to treat ADHD is critical. Neurofeedback for this purpose is intriguing and seems very reasonable.
Journal Article, January 08, 2007
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How Risky Are SSRIs During Pregnancy?
Serotonin affects pulmonary vascular tone; in theory, therefore, elevated levels of this neurotransmitter from serotonin reuptake inhibition could be problematic for developing lungs.
Journal Article, September 18, 2006
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After Two Failed Trials for Major Nonpsychotic Depression,What's Next?
The third wave of STAR-D reinforces current clinical practice. Do the results also encourage clinicians to turn to mirtazapine or nortriptyline exclusively for treatment of major depression?
Journal Article, July 17, 2006
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Helping Children By Helping Depressed Mothers
According to the STAR-D trial, treatment of maternal depression improved psychiatric diagnoses in their children.
Journal Article, May 03, 2006
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Psychopathology 10 Years Later in Children with ADHD
Lifetime prevalence of each of the psychiatric disorders evaluated was significantly higher in the ADHD group compared with controls except for psychosis, language disorder and encopresis.
Journal Article, March 08, 2006
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New Stories of How Genes and Life Events Interact in Depression
At least 10 allelic variants have now been identified for 5-HTTLPR. All deserve study. What might have been a simple and elegant story may ultimately prove to be elegant, but not quite so simple.
Journal Article, January 01, 2006
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Does VNS Work in Refractory Depression?
While, adjunctive VNS is not particularly effective acutely, response rates may increase with continued treatment. However, this treatment is expensive and invasive.
Journal Article, November 02, 2005
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Cognitive Therapy Prevents Future Suicide Attempts
Treatment targeted at suicidal behavior, rather than the underlying condition, is a powerful strategy for reducing risk for subsequent attempts.
Journal Article, September 07, 2005
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The Scent of a Woman
Do homosexual men and heterosexual women share a common pathway of sexual hypothalamic response?
Journal Article, July 21, 2005
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War is Hell
As suggested by this study of a simulated but reality-based exercise,ongoing demands of military personnel can lead to disastrous outcomes in physical, mental, and emotional health.
Journal Article, May 04, 2005
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Deep Brain Stimulation for Depression
Although too early to draw conclusions, deep brain stimulation of the subgenual region of the cingulate gyrus seems to modulate negative mood states.
Journal Article, March 24, 2005
