Journal Watch Neurology

Long-term Dual Antiplatelet Therapy for Lacunar Stroke Some specific ischemic stroke subtypes, such as lacunar stroke, may not benefit from long-term combination aspirin and clopidogrel therapy.
Journal Article, October 15, 2012
Deep Brain Stimulation for Parkinson Disease Which method of deep brain stimulation is most effective for patients with Parkinson disease?
Journal Article, August 28, 2012
Does Lowering Cholesterol Reduce Parkinson Disease Risk? Two large studies suggest disease-modifying and possible neuroprotective effects of statins in Parkinson's disease, but the results should be interpreted with caution.
Journal Article, June 01, 2012
Dementia Associated With Increased Rate of Hospitalization Does dementia increase the risk for hospitalization in elderly patients?
Journal Article, April 06, 2012
Dexpramipexole in ALS: Cautious Optimism Might the experimental drug dexpramipexole slow disease progression in ALS? Results of a Phase II trial are promising.
Journal Article, February 02, 2012
Prehypertension and the Continuum of Stroke Risk Is prehypertension associated with a greater risk of stroke?
Journal Article, December 01, 2011
Predicting Outcomes After Neonatal Hypoxic-Ischemic Injury Can the systematic use of brain MRI help to predict neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy?
Journal Article, September 30, 2011
Preventive Medication for Recurrent Stroke This comparative study of the selective thromboxane–prostaglandin receptor antagonist terutroban vs. aspirin in preventing recurrent stroke left aspirin standing as the gold standard.
Journal Article, August 05, 2011
Telemedicine for Stroke Care: The Finnish Experience Can a telemedicine system enable remote stroke practitioners to reliably evaluate patients when a bedside practitioner is not immediately available?
Journal Article, June 03, 2011
Validating PET Amyloid Imaging With Autopsy This important study demonstrates that PET scans using an amyloid imaging agent may serve as a diagnostic tool for Alzheimer's disease by accurately detecting amyloid beta plaque.
Journal Article, March 31, 2011
DHA Supplementation in Alzheimer Disease Does current evidence support recommendations of fish oil supplements for the prevention of dementia progression in Alzheimer's disease?
Journal Article, February 03, 2011
Cilostazol vs. Aspirin for Recurrent-Stroke Prevention Is the phosphodiesterase inhibitor cilostazol as effective as aspirin at preventing recurrent stroke?
Journal Article, December 09, 2010
Optimal Screening Strategy for Familial Intracranial Aneurysms This thought-provoking article presents a screening strategy for familial intracranial aneurysms based on a statistical simulation model.
Journal Article, September 30, 2010
Cholesterol Reduction and the Brain--Heart Connection This study provides support for the benefits of statin therapy after a stroke or transient ischemic attack, in terms of both brain and cardiac protection.
Journal Article, August 06, 2010
Prognosis of Comatose Survivors After Cardiopulmonary Resuscitation Is clinical assessment alone as good as electrophysiological testing in predicting outcomes of hypoxic coma?
Journal Article, June 18, 2010
Mediterranean Diet, Physical Activity, Cognitive Function, and Dementia What role does diet and physical activity play in age-related cognitive decline and dementia? Two studies provide some answers.
Journal Article, February 01, 2010
Plasmapheresis for Managing Natalizumab-Associated PML: A Risky Proposition These case reports highlight the dilemma faced by clinicians caring for multiple sclerosis patients who develop progressive multifocal leukoencephalopathy during natalizumab treatment.
Journal Article, November 24, 2009
The Enigma of Evening and Weekend Stroke There's no good time to have a stroke, but being admitted to a hospital for stroke on a weekend or evening might be particularly dangerous, even in hospitals with high-quality stroke care.
Journal Article, October 28, 2009
Is Benign Multiple Sclerosis Truly Benign? What is the extent of brain tissue damage and cognitive disability among patients with benign multiple sclerosis?
Journal Article, February 03, 2009
Migraine With Aura, Gene Polymorphisms, and Stroke Risk Is a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene associated with migraine (with or without aura) and with cardiovascular events (CVD, stroke and myocardial infarction)?
Journal Article, December 09, 2008

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