Journal Watch Dermatology

 
 
  • Do Fish and Birds Reduce Eczema in Infants? What is the prevalence of eczema among families with infants in Sweden? What are the triggers or risk factors for eczema among infants?
  • UVA-1 for Sclerotic Skin Disease: More Is Not Better Sclerotic skin diseases are challenging to treat due to limited treatment options. UVA-1 phototherapy is an option with 3 dosing regimens. Which dose most effectively treats sclerotic skin diseases?
  • Beta-Blocker Busts Infantile Hemangiomas Most infantile hemangiomas do not need to be treated unless a complication were to arise. Oral corticosteroids are first-line therapy, but what about a safer, easier, more predictable treatment?
  • Review of Atopic Dermatitis The hallmarks of atopic dermatitis are discussed, along with new treatment options for clinicians.
  • Universal Surveillance for MRSA - Does It Help? HA-MRSA disease is on the rise and every effort should be directed toward determining elements of infection control that are both beneficial and cost-effective.
  • Origin of Merkel Cell Carcinomas No Longer Murky The etiologic basis of Merkel cell carcinoma is uncertain. What causes this rare yet highly malignant skin cancer?
  • The Epidemiology of MRSA Invasive MRSA infections can be hospital and community-acquired. What are the three types of invasive MRSA infections? How frequently do they occur? Who is affected most and least often?
  • How Irritating are Alcohol Hand Rubs? Alcohol hand rub use is encouraged among medical personnel to prevent spread of infection, but they have a high incidence of hand dermatitis. Might the drying effect of alcohol irritate their skin?
  • Retinol Benefits Naturally Aged Skin Topical retinoids have been shown to improve the texture and fine lines of photodamaged skin. Does retinol improve signs of chronologic aging in skin?
  • The Lethal Thin Melanoma - Wolf in Sheep's Clothing Melanomas and related deaths on the rise, partly due to median thickness under 1 mm. This influences lymph node sampling. For predicting prognosis, molecular models will replace mathematical models.
  • Biologics for Psoriasis: The Second Generation IL-12//IL-23 antibody therapy compares favorable to the most effective currently available psoriasis therapy with few adverse effects. Phase III confirmation needed.
  • New Warning Issued for Rituximab Case reports of PML from new biological agent adds to concern about this class of drugs reserved for hard to manage inflammatory conditions or for those who develop toxicity from traditional meds.
  • UVA Radiation: More Serious Than Previously Thought Findings of this important study suggest that UVA radiation is more likely to cause DNA mutations, and therefore long-term risk of skin cancer, than previously thought.
  • When Sutures Get Wet Routine recommendation to keep wounds dry for 48 hours called into question by this trial. However, high infection rate for both study groups may render results erroneous or at least dubious.
  • Low-Dose Isotretinoin for Acne Vulgaris Per Israeli study, low-dose isotretinoin may be an option to treat moderate acne. But, there are several caveats like need for long-term trials and special concerns for women with refractory acne.
  • Endovenous Laser Treatment vs. Vein Stripping In a German trial, subjects (serving as their own control) clearly preferred laser treatment over traditional stripping of the GSV. Longer wavelength lasers should reduce side effects even further.
  • Excimer Laser vs. Pulsed-Dye Laser for Psoriasis PDL advantages (namely, fewer treatments and fewer side effects) do not compare to the better effectiveness of excimer laser. But, could PDL be of value for those who fail excimer-laser?
  • Sometimes Unnecessary to Suture Punch Biopsy Sites Second-intention healing may be as good as sutures for 4 mm punch biopsy sites but not for 8 mm sites. Patients with the larger size lesions report more pain and less satisfaction with gel foam.
  • The Melanoma Epidemic Report concludes that true occurrence of melanoma has not increased, only diagnosis of the disease. But, commentator eloquently argues that this conclusion cannot be drawn from data presented.
  • Does Isotretinoin Cause Depression? Results of this study showed no difference in risk for depression or suicide between isotretinoin and conservative acne therapy in small group of teenagers.