Critical Issues

Sleep and Delirium in the ICU: Rest for the Weary? New studies were recently published evaluating ramelteon and dexmedetomidine for delirium and sleep quality in ICU patients. Dr Aaron Holley offers his perspective.
Experts And Viewpoints, October 2018
A New Definition for Emphysema A new study has identified a clinically relevant definition for emphysema using CT imaging.
Experts And Viewpoints, September 2018
Prone Positioning Before ECMO Is 'Underutilized' Dr Aaron Holley discusses prone positioning before ECMO, with a focus on the EOLIA trial.
Experts And Viewpoints, August 2018
A Negative APRV Trial in ARDS When should airway pressure release ventilation be used over low-tidal-volume ventilation for acute respiratory distress syndrome? Results of the latest trials are analyzed here.
Experts And Viewpoints, June 2018
Should You Consider Prone Positioning Before ECMO? Dr Aaron Holley on new data on prone positioning for patients with acute respiratory distress challenges, as well as some preconceived notions, including his own.
Experts And Viewpoints, June 2018
Supplemental Oxygen Has Limited Powers Should you reconsider writing oxygen prescriptions? Dr Holley discusses a new review on home oxygen therapy for COPD.
Experts And Viewpoints, May 2018
Limb Muscle Dysfunction After Acute Exacerbation of COPD There are no short cuts when it comes to managing limb muscle dysfunction associated with acute exacerbation of chronic obstructive pulmonary disease.
Experts And Viewpoints, March 2018
Clinical Presentations and Treatment Implications of Asthma Dr Aaron Holley comments on a new review of eosinophilic and noneosinophilic asthma.
Experts And Viewpoints, March 2018
Pros and Cons of Extracorporeal Membrane Oxygenation for ARDS Dr Holley reviews arguments made for and against extracorporeal membrane oxygenation (ECMO) as first-line therapy for acute respiratory distress syndrome.
Experts And Viewpoints, January 2018
Protocolized APRV Versus Assist Control for ARDS A recently published, randomized trial compared APRV versus the current standard of care, low-tidal-volume ventilation. Will these results change the minds of skeptics?
Experts And Viewpoints, November 2017
Few Eligible ARDS Patients Receive Low Tidal Volume Ventilation Dr Holley summarizes a survey reporting that while a majority of physicians support use of low tidal volume ventilation for acute respiratory distress syndrome, few initiate it.
Experts And Viewpoints, August 2017
With Hypercapnic Respiratory Failure, Comorbidities Common Patients admitted to the ICU with hypercapnic respiratory failure have multiple comorbid diseases. Make the diagnosis before admission, says Dr Holley.
Experts And Viewpoints, August 2017
What Happens to Patients After They Leave the ICU Dr Holley reviews a new study that tracked outcomes at 6 and 12 months post ICU admission for acute respiratory distress syndrome.
Experts And Viewpoints, June 2017
Which Score to Use When Screening for Sepsis on the Wards Dr Holley reviews a new study that compared SIRS, qSOFA, and the Modiﬁed (MEWS) and National Early Warning Score (NEWS) screenings.
Experts And Viewpoints, April 2017
Why Volume-Controlled Ventilation May Not Be Safe Dr Holley reviews a new study that investigated volume-controlled ventilation in animal models and one patient case.
Experts And Viewpoints, March 2017
How to Interpret a Diffusion Capacity of the Lung for Carbon Monoxide Can POC tests provide reliable hemoglobin measurements for DLCO calculation? Dr Holley reviews a new study.
Experts And Viewpoints, March 2017
Achieving Patient/Ventilator Synchrony -- Good Luck Dr Aaron Holley comments on a study that characterizes the effects of ventilator mode and tidal volume on patient/ventilator synchrony.
Experts And Viewpoints, December 2016
Does Treating Mild OSA Lessen Daytime Sleepiness? Dr Aaron Holley explains the rationale for his opinion on treating mild obstructive apnea.
Experts And Viewpoints, November 2016
Ultrasound to Assess Volume Status--Why Bother? Why use an expensive test to find out whether the patient will respond to a fluid bolus, when a passive leg raise is just as helpful?
Experts And Viewpoints, November 2016
Transfusion Thresholds: Is the Pendulum Swinging Back? Aaron Holley discusses the latest transfusion thresholds for critical care patients, emphasizing areas of continuing controversy.
Experts And Viewpoints, November 2016

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