Critical Issues

Are Compression Devices Effective at Reducing DVT Risk? A comparison with chemoprophylaxis failed to see an advantage, but according to Dr Aaron Holley, several key questions remain unanswered.
Experts And Viewpoints, May 2019
IPAF: Heterogeneity Hurts Clinical Utility A pro-con debate surrounds the definition of interstitial pneumonia with autoimmune features.
Experts And Viewpoints, April 2019
Changes to Methacholine Challenge May Be Difficult to Apply Dr Aaron B. Holley on how the medical industry can step up to make this easier on everyone.
Experts And Viewpoints, March 2019
Diagnosing Obstructive Sleep Apnea: The Glass is Half Empty Dr Aaron Holley turns a cynical eye to a new study endorsing the liberal, arousal-based definition of hypopnea.
Experts And Viewpoints, February 2019
Another ICU Intervention That May Not Work as Advertised Dr Aaron Holley on the continued debate over whether PPIs truly limit GI bleeding in this setting.
Experts And Viewpoints, January 2019
Despite What We May Think, Diagnosing Asthma Isn't Easy Dr Aaron Holley on the surprising challenges in diagnosing this increasingly prevalent condition, and how to surmount them.
Experts And Viewpoints, November 2018
RBC Transfusion and Cardiac Surgery: Be Strict and Restrict? Should packed RBC transfusions be given liberally to patients undergoing cardiac surgery? Or should they be restricted to a low hemoglobin threshold?
Experts And Viewpoints, November 2018
Sleep and Delirium in the ICU: Rest for the Weary? New studies were recently published evaluating ramelteon and dexmedetomidine for delirium and sleep quality in ICU patients. Dr Aaron Holley offers his perspective.
Experts And Viewpoints, October 2018
A New Definition for Emphysema A new study has identified a clinically relevant definition for emphysema using CT imaging.
Experts And Viewpoints, September 2018
Prone Positioning Before ECMO Is 'Underutilized' Dr Aaron Holley discusses prone positioning before ECMO, with a focus on the EOLIA trial.
Experts And Viewpoints, August 2018
A Negative APRV Trial in ARDS When should airway pressure release ventilation be used over low-tidal-volume ventilation for acute respiratory distress syndrome? Results of the latest trials are analyzed here.
Experts And Viewpoints, June 2018
Should You Consider Prone Positioning Before ECMO? Dr Aaron Holley on new data on prone positioning for patients with acute respiratory distress challenges, as well as some preconceived notions, including his own.
Experts And Viewpoints, June 2018
Supplemental Oxygen Has Limited Powers Should you reconsider writing oxygen prescriptions? Dr Holley discusses a new review on home oxygen therapy for COPD.
Experts And Viewpoints, May 2018
Limb Muscle Dysfunction After Acute Exacerbation of COPD There are no short cuts when it comes to managing limb muscle dysfunction associated with acute exacerbation of chronic obstructive pulmonary disease.
Experts And Viewpoints, March 2018
Clinical Presentations and Treatment Implications of Asthma Dr Aaron Holley comments on a new review of eosinophilic and noneosinophilic asthma.
Experts And Viewpoints, March 2018
Pros and Cons of Extracorporeal Membrane Oxygenation for ARDS Dr Holley reviews arguments made for and against extracorporeal membrane oxygenation (ECMO) as first-line therapy for acute respiratory distress syndrome.
Experts And Viewpoints, January 2018
Protocolized APRV Versus Assist Control for ARDS A recently published, randomized trial compared APRV versus the current standard of care, low-tidal-volume ventilation. Will these results change the minds of skeptics?
Experts And Viewpoints, November 2017
Few Eligible ARDS Patients Receive Low Tidal Volume Ventilation Dr Holley summarizes a survey reporting that while a majority of physicians support use of low tidal volume ventilation for acute respiratory distress syndrome, few initiate it.
Experts And Viewpoints, August 2017
With Hypercapnic Respiratory Failure, Comorbidities Common Patients admitted to the ICU with hypercapnic respiratory failure have multiple comorbid diseases. Make the diagnosis before admission, says Dr Holley.
Experts And Viewpoints, August 2017
What Happens to Patients After They Leave the ICU Dr Holley reviews a new study that tracked outcomes at 6 and 12 months post ICU admission for acute respiratory distress syndrome.
Experts And Viewpoints, June 2017

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