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  • Lipid Management: The Ins and Outs of Inclisiran   Christopher V. DeSimone, MD, PhD, and Stephen L. Kopecky, MD, discuss lipid management and the use of inclisiran, an siRNA drug that inhibits the RNA from making PCSK9.
  • Leaks After Percutaneous LAAO and Stroke Risk   Drs Christopher DeSimone and Mohamad Alkhouli discuss the prevalence of leaks following percutaneous left atrial appendage closure and the implications for stroke risk.
  • Bioprosthetic Valve Thrombosis: A Perhaps Not So Rare Complication   Dr Christopher DeSimone speaks with expert Dr Sorin Pislaru on how thrombosis contributes to valve failures and reoperations, and what can be done to avoid it.
  • Managing Hypertrophic Cardiomyopathy: New Guidelines and Drugs   Cardiologist Christopher DeSimone speaks with Steve Ommen about new AHA/ACC guidelines, emerging treatments, and the importance of focused HCM care.
  • AF Ablation Latest: Whom to Treat and How Early to Intervene   Drs Thomas Munger and Peter Noseworthy weigh the results of recent data on early intervention in AF in light of CABANA and other trials.
  • Is Red Meat Bad for Your Heart?   Drs Kopecky and Lopez-Jimenez discuss the research on health effects of eating processed and unprocessed meat in the wake of a controversial guideline.
  • Is Coronary Plaque Regression Possible?   Regression of some types of coronary plaque is possible but not 'simplistic.' Drs Lopez-Jimenez and Kopecky offer their expert insights.
  • Cardiologists, Oncologists Desperately Need Your Help   Oncologists and cardiologists need to collaborate to optimize outcomes for patients with cancer and long-term survivors. Will a new subspecialty emerge?
  • Pros and Cons of LAA Occlusion Devices vs Anticoagulation Which is more effective at stopping cardiac emboli from forming in the left atrial appendage: the Watchman or a novel oral anticoagulant? Mayo Clinic heart rhythm experts discuss the data.
  • Is Sirolimus the Superior Heart Transplant Antirejection Therapy?   With 20 years of experience with sirolimus, two Mayo Clinic experts describe the advantages and disadvantages of this antiproliferative drug in patients after heart transplant.
  • Paclitaxel-Coated Devices on Pause for Patients With PAD   Why has Mayo Clinic placed a temporary moratorium on paclitaxel-coated devices for PAD? Radiology and cardiology experts discuss the controversy and what it will take to settle the issue.
  • Are e-Cigarettes Safer Than Tobacco? It's Complicated   Do e-cigarettes help people quit smoking tobacco? Maybe, but they come with risks, say Mayo Clinic experts.
  • Entering the TWILIGHT Zone of DAPT Duration   Experts from the Mayo Clinic discuss the impact of TWILIGHT, a comparison of ticagrelor monotherapy vs dual-antiplatelet therapy in post-PCI patients.
  • Virtual Reality in Medicine: Beyond Bulky Goggles   A trainee can stand in the surgeon's place instead of straining to see what's going on -- just one of the possibilities of virtual and immersive technologies in medicine, according to Mayo 's Dr Suraj Kapa.
  • The Lowdown on Lipoprotein(a)   Drs Tom Allison and Stephen Kopecky discuss current understanding of this unique subclass of lipoprotein and how to address elevated levels.
  • ISCHEMIA: Do Baseline Data Hint at Triumph for OMT?   The success of OMT and the decline of patients with severe ischemia may make it difficult for ISCHEMIA to show benefit for revascularization, predicts Mayo Clinic's Raymond Gibbons, MD.
  • Noninvasive Imaging for Suspected CAD: Which Test When?   Dr Anavekar explains the pros and cons of current noninvasive imaging modalities and his preferences for inpatient and outpatient assessment of CAD.
  • Today's Cardiac Intensive Care Unit--Not Your Mother's CCU   Cardiac intensive care units have evolved rapidly in recent years. Drs Barsness and Acharya discuss unique training and resource requirements for a model CICU.
  • Sleep Apnea and Cardiovascular Disease   Dr Virend Somers sits down with Dr Jay Widmer to parse the relationships between central and obstructive sleep apnea and cardiovascular diseases--and the best treatment strategies for each.
  • The Scoop on the New Syncope Guidelines   Drs Win-Kuang Shen and Peter Noseworthy discuss key recommendations on the diagnosis and management of syncope as published in the new ACC/AHA guidelines.