Interventional Cardiology Resource Center Heartwire News High and Low

• When EDs Close, Patients at Nearby Hospitals Suffer Low-occupancy emergency departments (EDs) may be better able to absorb extra patients than busier high-occupancy EDs, the researchers say.
  Medscape Medical News, September 2019
• ESC 2019SYNTAXES: CABG for Best 10-Year Survival in Multivessel Disease Longer-term outcome data from SYNTAX trial give a 'clear mandate' to expand the role of CABG and to adopt a more cautious indication for PCI in multivessel disease, one expert says.
  Medscape Medical News, September 2019
• ESC 2019DAPA: Early ICD After Primary PCI-Treated STEMI Saves Lives Patients with STEMI who underwent early ICD implantation had a survival benefit 10 years later, compared with standard medical care, although questions remain over patient selection.
  Medscape Medical News, September 2019
• ESC 2019Genetic Testing Spots Clopidogrel Responders After PCI for STEMI Guidelines for the management of acute STEMI patients undergoing PCI may need to be revised after a genotype-guided protocol giving clopidogrel to responders reduced bleeding rates, say experts.
  Medscape Medical News, September 2019
• Heart Surgery Long-Term Mortality Rate Higher for Women Women have worse long-term mortality after coronary-artery bypass grafting (CABG) and combined CABG/mitral-valve surgery, while mortality risk factors are different for men and women, according to new findings.
  Reuters Health Information, August 2019
• ESC 2019AFIRE Backs Less Antiplatelet Use With NOAC in AF, Stable CAD Helping buttress a thin evidence base, the randomized trial argues against pairing a novel oral anticoagulant with an antiplatelet in stable CAD with AF, barring PCI or CABG in the last year.
  Medscape Medical News, September 2019
• ESC 2019DANAMI-2: PCI Still Beats Lysis in STEMI Even 16 Years On Physicians 'should feel confident' that offering primary PCI to patients with STEMI in an invasive center will offer long-term benefits over giving fibrinolysis at a local hospital, say Danish researchers.
  Medscape Medical News, September 2019
• ESC 2019ISAR-REACT 5: Prasugrel Bests Ticagrelor in ACS In this 'landmark' head-to-head trial, 1-year survival free of MI or stroke was better in patients with ACS who received prasugrel rather than ticagrelor -- contrary to the researchers' hypothesis.
  Medscape Medical News, September 2019
• ESC 2019THEMIS: A Role for Ticagrelor in Diabetic Patients With Prior PCI? For patients with type 2 diabetes and stable coronary artery disease, ticagrelor had no net clinical benefit in the overall trial, but results in patients with a previous PCI were more promising.
  Medscape Medical News, September 2019
• ESC 2019COMPLETE: Better Outcome With PCI in Nonculprit Lesions After STEMI New data show intervention in nonculprit lesions after STEMI in patients with multivessel disease reduced CV death, recurrent MI, and ischemia-driven revascularization vs a culprit-lesion-only strategy.
  Medscape Medical News, September 2019
• ESC 2019Stable CAD Reconsidered: ESC Chronic Coronary Syndrome Guideline The document sees chronic coronary disease as a dynamic process poorly served by the term 'stable' CAD. It defines CCS by six clinical scenarios with different diagnostic and therapeutic issues.
  Medscape Medical News, September 2019
• ESC 2019Early Evolocumab in Acute Coronary Syndrome Safe, LDL Plummets EVOPACS, the first randomized trial of a PCSK9 inhibitor in this very high-risk setting, hints earlier use may be warranted, but experts agree that a dedicated CV outcomes trial is needed first.
  Medscape Medical News, August 2019
• ESC 2019Bleeding in ACS Patients on DAPT Should Prompt Cancer Search Unexplained bleeding in patients discharged on DAPT after acute coronary syndrome treated with PCI is associated with increased cancer risk, new research suggests.
  Medscape Medical News, August 2019
• Expert Panel Algorithm for Post-TAVR Conduction Disturbances TAVR carries a risk for postprocedure conduction disturbances. This first-time algorithm stratifies patients and recommends strategies for assessing and managing these arrhythmias.
  Medscape Medical News, August 2019
• Use of Prophylactic Cranial Irradiation for Extensive-Stage Small-Cell Lung Cancer May Be Dropping Prophylactic cranial irradiation (PCI) for patients with extensive-stage small-cell lung cancer (ES-SCLC) appears to have become less common in the U.S., according to a new survey.
  Reuters Health Information, August 2019
• No Survival Benefit with Myocardial Viability After CABG: STICH Past research suggested that myocardial viability might aid survival in coronary bypass surgery patients. This study found no long-term survival benefit but modest improvement in ejection fraction.
  Medscape Medical News, August 2019
• Alert FDA Slaps Class I Recall on Sapien 3 Ultra for TAVR The class I recall of the transcatheter aortic valve replacement (TAVR) device follows an urgent field warning about burst balloons issued last month by device maker, Edwards Lifesciences.
  News Alerts, August 2019
• Alert FDA Approves New Form of HF Device Therapy, the Barostim Neo
  FDA Approvals, August 2019
• Alert FDA Expands Approval for TAVR Valves to Low-risk Patients The Sapien 3 and Sapien 3 Ultra and the CoreValve Evolut R and CoreValve Evolut PRO were previously indicated only in patients at intermediate or higher surgical risk.
  FDA Approvals, August 2019
• Higher Mortality With Off-Pump CABG in Left Main Disease Post hoc analysis from the EXCEL trial indicates off-pump surgery was associated with increased 3-year all-cause death and more incomplete revascularization than on-pump in left main disease.
  Medscape Medical News, August 2019