Interventional Cardiology Resource Center Heartwire News High and Low

• New ACC/AHA Performance, Quality Measures for Cardiac Rehab Notable new performance measures advise referral to cardiac rehabilitation for patients with heart failure with reduced ejection fraction and include measures to assess enrollment.
  Medscape Medical News, April 2018
• EHRA 2018MORE-CRT MPP: Multipoint Pacing Disappoints in Phase 1 The trial hints, however, at a benefit over standard biventricular pacing in patients in whom multipoint pacing was optimized.
  Medscape Medical News, March 2018
• ACC 2018Shortening Dual Antiplatelet Therapy Ups MI Risk in ACS Although the SMART-DATE trial met its noninferiority composite endpoint, increased MI with shorter treatment led to the conclusion that 12 months or longer of DAPT should remain standard of care.
  Medscape Medical News, March 2018
• ACC 2018New Studies Encourage Clopidogrel Genotyping Two new studies suggest genotyping patients with ACS or those undergoing PCI to identify poor clopidogrel responders influences decision making on drug therapy by the interventionalist and may lead to benefits in outcomes.
  Medscape Medical News, March 2018
• ACC 2018SECURE-PCI: 'Statin Loading' in ACS Doesn't Cut 30-Day Event Risk But 30-day events dropped significantly after two big atorvastatin doses in one predefined subgroup of the trial's broad acute coronary syndrome population, a secondary but enticing result.
  Medscape Medical News, March 2018
• ACC 2018TREAT: Ticagrelor Safe in STEMI Patients After Fibrinolysis Randomized but open-label data show ticagrelor was noninferior to clopidogrel in terms of major bleeding at 30 days for patients with ST-segment elevation MI.
  Medscape Medical News, March 2018
• ACC 2018COMBO Stent Impresses at 1 Year in 'All-Comers' Registry Although randomized results are still awaited, real-world registry results with the COMBO stent, designed to regenerate endothelium and reduce in-stent thrombosis, are 'exciting,' researchers say.
  Medscape Medical News, March 2018
• Trials Headlining ACC Session 'Promise to Be Practice Changing' ACC program directors point to two trials that, if positive, will change practice, including one that studied a PCSK9 inhibitor in secondary prevention and one on use of a defibrillator vest early after MI.
  Medscape Medical News, March 2018
• Long-term Survival Edge for On-Pump vs Off-Pump Bypass Surgery But was the difference clinically meaningful? 'It is time for the debate to move on,' says an editorial. Rather, it's time to discuss which patients 'may benefit more from one approach or the other.'
  Medscape Medical News, March 2018
• Alert FDA Approves First 2.0-mm Drug-Eluting Stent in US The approval taps into a patient population with an unmet clinical need and expands Medtronic's device platform from sizes 2.0 mm to 5.0 mm.
  FDA Approvals, February 2018
• Atrial Fib After Bypass Packs Long-term Deleterious Punch The arrhythmia was found almost exclusively in patients treated with bypass surgery and was associated with significantly worse short- and long-term outcomes.
  Medscape Medical News, February 2018
• Safety Similar With Radial vs Ulnar Approach in Cardiac Cath Major adverse cardiovascular event rates were not significantly different from those obtained with radial artery access, but transulnar access remains on the fringe of the PCI world.
  Medscape Medical News, February 2018
• Alert FDA Expands Impella Pump Indications in High-Risk PCI, Shock The catheter-delivered temporary ventricular support pumps are now indicated for high-risk PCI regardless of LV function, and for shock secondary to cardiomyopathy, Abiomed announced.
  FDA Approvals, February 2018
• Subpar Medical Therapy Common Even in High-Profile Trials Despite the known benefits of cardioprotective medications, a meta-analysis suggests adherence is poor in participants undergoing bypass surgery and PCI and is off-kilter between the two procedures.
  Medscape Medical News, February 2018
• Sleep Apnea Might Put CABG Patients at Risk for Ventricular Arrhythmias Sleep-disordered breathing (SDB) is associated with abnormal cardiac repolarization before coronary artery bypass graft surgery (CABG), according to new research.
  Reuters Health Information, February 2018
• High Death, Hospitalization Rates With Chronic Ischemic CV Disease Mortality and hospitalization rates at 6 months are high among patients with chronic ischemic cardiovascular disease (CICD), according to initial findings from the European Society of Cardiology (ESC) CICD Pilot Registry.
  Reuters Health Information, January 2018
• Surgical LAA Occlusion in AF Seen to Cut Thromboembolic Risk Closing the left atrial appendage should now be the standard of care at cardiac surgeries in patients with AF, say researchers, but it remains unknown whether oral anticoagulation is still needed.
  Medscape Medical News, January 2018
• National Analysis Questions Role of First-Line PCI in SCAD The all-female acute MI study found higher in-hospital mortality in those with spontaneous coronary artery dissection but is unlikely to be the last word on how best to manage these high-risk patients.
  Medscape Medical News, January 2018
• Obesity Paradox Prevails for PCI in Women Pooled analyses in a large all-female cohort revealed higher mortality risk at either end of the BMI spectrum and underlined the need for special attention to underweight women undergoing PCI.
  Medscape Medical News, January 2018
• PCI Incomplete Revascularization Outcomes Vary by Coronary Anatomy Several specific anatomic features in coronary arteries that are incompletely revascularized at PCI can raise an already increased risk for death within 3 years, suggest New York state data.
  Medscape Medical News, January 2018