Clostridium difficile Infection News

• Fecal Transplant Trial for IBS Shows Lasting Response Investigators also find that changes in 10 bacteria were significantly correlated with IBS symptoms.
  Medscape Medical News, July 06, 2022
• C. diff: How Did a Community Hospital Cut Infections by 77%? It took teamwork by a wide range of professional staff and support from leadership.
  Medscape Medical News, May 26, 2022
• DDW 2022 Fidaxomicin Favored Over Vancomycin in Real-World C diff Study Researchers compared the agents for treating both initial and recurrent Clostridioides difficile infections in a Medicare population.
  Medscape Medical News, May 24, 2022
• DDW 2022 Bacterial Cocktail, Spores Counter Recurrent C difficile Both the complex mixture and specific, refined spores may hold promise in reducing recurrences, and may circumvent fecal microbiota transplants.
  Medscape Medical News, May 24, 2022
• Understanding Toxin Testing Results for C diff Testing stool samples for C difficile exotoxins A and B is frequently used to diagnose a C difficile infection, but clinicians need a greater understanding of what the results mean.
  Medscape Medical News, May 06, 2022
• Novel Antibiotic Shows Promise for C diff Infection A novel antibiotic therapy for Clostridioides difficile infection, currently dubbed CRS3123, has demonstrated narrower selectivity and reduced bacterial derangement in the gut compared with other antibiotics.
  Medscape Medical News, May 06, 2022
• Black, Senior Patients More Likely to Get Unneeded Antibiotics A new study that looked at 7 billion trips to healthcare centers found that antibiotics continue to be far overprescribed, especially among Black and senior patients.
  WebMD Health News, April 20, 2022
• Asymptomatic C. difficile Carriers May Infect Their Families Hospitalized asymptomatic C. difficile carriers may infect people they live with after they return home, new research suggests.
  Medscape Medical News, April 13, 2022
• Engineered Bacteria Could Protect Gut from Antibiotics: Study 'The problem comes when interventions such as medications or particular kinds of diets affect the composition of the microbiota and create an altered state, called dysbiosis.'
  WebMD Health News, April 13, 2022
• What's the Future of Microbiome Therapies in CDI, Cancer? Preventive treatments for C difficile recurrence are in phase 3 trials. Oncologists are also investigating microbiome-based differences in treatment response.
  Medscape Medical News, March 18, 2022
• Aerosolized Hydrogen Peroxide Can Significantly Reduce C. difficile Infections Aerosolized hydrogen peroxide is a new tool in fighting C. difficile in healthcare settings.
  Medscape Medical News, March 18, 2022
• Are 'Antibiotic Diets' Good Practice? Researchers are debating whether probiotics and microbiome-boosting foods can help our guts recover during periods of antibiotic use, allowing patients to stay on course with treatment.
  Medscape Medical News, March 16, 2022
• C difficile Vaccine: CLOVER Trial Shows Mixed Results There's mixed news from Pfizer on results from the CLOVER trial of their candidate vaccine for preventing C diff infection.
  Medscape Medical News, March 08, 2022
• ECCO 2022 'Superdonor' Samples Don't Increase FMT Success in UC RESTORE-UC trial results contradict positive results seen in previous trials despite using highly standardized "superdonor" samples.
  Medscape Medical News, February 28, 2022
• C Difficile: New Vancomycin-Resistant Strains Raise Concerns The detection of a marked increase in unrecognized strains of C difficile suggests a 'pressing need' to understand mechanisms.
  Medscape Medical News, February 04, 2022
• Donor-Derived Strains Predict FMT Response for Ulcerative Colitis Core strains from human donors limited ulcerative colitis in mouse models, which may shape strategies for more effective microbial therapy.
  Medscape Medical News, December 06, 2021
• 'Forgotten Antibiotic' Better Than Cefotaxime in Febrile UTIs? The rich, commensal microbiota of the distal gut is a breeding ground for resistant microorganisms, and collateral damage to the human microbiota can occur with use of antibiotics.
  Medscape Medical News, November 02, 2021
• ACG 2021 A Pill for C difficile Works by Increasing Microbiome Diversity Freeze-dried human stool may offer advantages for the treatment of C difficile infections.
  Medscape Medical News, October 24, 2021
• Fecal Transplants May Improve Resistance to Melanoma Therapy 'The big question...is why and how does FMT work, and how can we make the response better?' asked Dr Teri Greiling of Oregon Health & Science University.
  Medscape Medical News, October 21, 2021
• Gut Bacteria May Fuel Prostate Cancer Treatment Resistance During prostate cancer treatment, some gut bacteria start making hormones that may support cancer growth and treatment resistance.
  WebMD Health News, October 15, 2021