Nature Clinical Practice Urology

 
 
  • Open Partial Nephrectomy The author argues that nephron-sparing surgery is under-used, and that the trend for urologists to adopt laparoscopic radical nephrectomy could have important consequences for overall renal function.
  • Bladder Outlet Obstruction in Women This review discusses the symptoms associated with bladder outlet obstruction in women and the role of urodynamic testing in diagnosis. Iatrogenic BOO following incontinence surgery is also discussed.
  • Should combination therapy be standard for BPH? Does a combination of two drugs provides greater symptomatic relief than standard monotherapy for patients with benign prostatic hyperplasia? Dr. Fitzpatrick reviews the evidence.
  • Osteoporosis during hormone therapy for prostate cancer This review outlines the mechanisms involved in bone loss associated with GnRH agonists and discusses how to treat and prevent osteoporosis in this group of patients.
  • MRI Evaluation in Prostate Cancer Prostate cancer screening, staging and management protocols are topics of continuous debate and evaluation. This Case Study demonstrates the value of endorectal MRI in the initial staging and work-up.
  • Questionnaires vs Urodynamics in Evaluating LUTS When seeking a diagnosis in patients complaining of urinary symptoms there is a variety of measures that can be used. The appropriate use of these diagnostic tests is discussed in this Primer Review.
  • Short- or Long-Course Radiotherapy for Bone Metastases? The optimal radiotherapy schedule for the palliation of painful bone metastases is a matter of debate. Mary Gospodarowicz discusses a phase III trial that compared short- and long-course radiotherapy.
  • Bladder Dysfunction Associated With Multiple Sclerosis Vinay Kalsi and Clare Fowler review the neurologic control of bladder function and the different treatments available to patients with multiple sclerosis who experience lower urinary tract symptoms.
  • Scandinavian Prostatectomy Study Illustrates Two Common Errors This article discusses 2 common statistical errors: accepting the null hypothesis and misinterpreting the lower power of overall vs cancer-specific survival.
  • Priapism Associated With Hematologic Dyscrasias This review of priapism in men with hematologic dyscrasias discusses the management of ischemic priapism, and stresses the need for prompt treatment in order to preserve erectile function.
  • Treatment of Uncomplicated Cystitis in Women Widespread use of antimicrobials continues to promote the problem of antimicrobial resistance. Increasing resistance to trimethoprim/sulfamethoxazole and fluoroquinolones prompted one team of researchers to investigate amoxicillin/clavulanate as an alternative treatment for acute uncomplicated cystitis.
  • The Natural History of Small Renal Masses The incidental finding of small renal masses is becoming a more common event as a result of widely used cross-sectional imaging techniques.
  • Overactive Bladder: Drug Therapy Versus Nerve Stimulation The 2 primary management strategies of overactive bladder are drug therapy and sacral neurostimulation. Drs. Pathak and Aboseif discuss the relative merits, and drawbacks, of these 2 approaches.
  • Managing the Risk of Long-Term Warfarin Anticoagulation Therapy Paul Daniels reviews the risk of hemorrhaging in patients receiving long-term anticoagulation therapy, and suggests management options that take into account the risk of venous thromboembolism.
  • Artificial Neural Networks: Has the Time Come for Their Use in Artificial neural networks have been developed for various applications in prostate cancer management, but their use remains controversial. In this Viewpoint, authors present the case for ANNs.
  • A Novel Surgical Technique for the Management of Peyronie’s John Mulcahy discusses a new surgical procedure recently described by Austoni and co-workers that solves the problem of penile retraction in men with Peyronie's disease.
  • Sleep-Related Painful Erections After describing the case of a 45-year-old man with sleep-related painful erection, the authors discuss the clinical presentation of this rare condition, as well as its diagnosis and management.
  • Can Hypnosis Reduce Distress and Improve Compliance With Voiding In a recent study, hypnosis effectively reduced distress children experienced during voiding cystourethrogram. Christian Radmayr discusses the challenges of performing painful procedures in children.
  • Penile Enlargement Surgery-Fact or Illusion? Penile enlargement surgery, though extremely popular, receives very little formal scrutiny. The authors raise questions about the safety, and indeed efficacy, of this procedure.
  • Does Preservation of the Neurovascular Bundle During Radical The authors review a study from the Journal of Urology on the risks associated with preserving the neurovascular bundle during radical prostatectomy. Does this technique compromise cancer control?