Hematology Articles

 
 
  • DNA Damage May Underlie Alcohol Link to Cancer Risk The link between alcohol and cancer risk may be due to ethanol causing DNA damage, which may be amplified in individuals lacking the enzyme to break down acetaldehyde, suggest UK study findings.
  • Drone Transport of Biological Samples Over Long Distances Is it feasible to transport biological samples over long distances by drone? This study investigated how temperature, time and humidity effect sample stability.
  • Rituximab Maintenance a 'Relevant' Option in Elderly CLL Patients Two-years of rituximab maintenance therapy can prolong remission in selected elderly patients with chronic lymphocytic leukemia (CLL) in first remission after an abbreviated front-line course of fludarabine, cyclophosphamide and rituximab (FCR), according to a study from France.
  • Sickle Cell Patients and Doctors Face a 'Fight for Everything' To sickle cell patients and their families — most of whom are African-American — efforts to fight the disease appear slow, underfunded, ineffective or too limited in scope, perpetuating disparities that have existed for more than a century.
  • Biomarkers for Drug-induced Liver Injury This review examines the potential use of both traditional and new candidate biomarkers for prediction, detection, and risk management of drug-induced liver injury.
  • Important CV Risk Seen With Carfilzomib in Multiple Myeloma Carfilzomib, approved for previously treated multiple myeloma, is associated with a significantly greater risk for all-grade and high-grade cardiovascular events and requires vigilance when used.
  • Ganetespib, Paclitaxel, Trastuzumab for HER2+ Breast Cancer Early research finds that ganetespib added to paclitaxel and trastuzumab shows promise for heavily pretreated patients with HER2+ breast cancer.
  • Sepsis-Related Diagnosis Impacts Interventions and Outcomes How might the presence or absence of a sepsis-related diagnosis impact ED interventions and in-hospital outcomes?
  • ASH CAR T Cells: Exciting, but Who Is Going to Cover Costs? An analysis of Medicare reimbursement shows that even with a 400% markup, hospitals will be hit with a financial loss.
  • Cardiovascular Complications of Cancer Therapy Cancer therapy can have serious cardiovascular complications. Learn about the cardiac effects of commonly used chemotherapies and how best to prevent and manage them in this overview.
  • Diagnostic and Prognostic Biomarkers for Mesothelioma Although validation is needed, these biomarkers show the most promise in malignant mesothelioma.
  • Thrombolysis in Postoperative Stroke Recent surgery is generally considered a contraindication to intravenous thrombolysis. Can IVT be performed safely in patients with postoperative stroke?
  • Low-dose Methotrexate: Determinants for Adverse Events What are the relative risks of adverse events in patients exposed to low-dose methotrexate vs. placebo, and what factors might predispose patients to these events?
  • Physical Activity Helps Lymphoma Patients Live Longer For lymphoma patients, increasing physical activity lowers the risk of death from any cause and from lymphoma, according to results of an observational study.
  • CD200 Expression in Neuroendocrine Neoplasms Might CD200 be a potential therapeutic target for neuroendocrine neoplasms?
  • Next Generation Approaches for Tumor Vaccination While early studies were disappointing, cancer vaccines are making a resurgence due to advances in precision medicine.
  • ASH Simple Strategies Can Reduce Blood Transfusions for Anemia The Choosing Wisely campaign calls for judicious use of red blood cell transfusions for iron deficiency anemia; simple strategies reduced the number of inappropriate transfusions.
  • Lapatinib With Foretinib in HER2+ Metastatic Breast Cancer Early research finds limited activity with the combination of lapatinib and foretinib for advanced HER2+ breast cancer.
  • Coffee Consumption and Health While many observational studies have made claims about the benefits of coffee consumption, this study aimed to systematically assess higher level evidence of the effects of coffee on health.
  • ASH Daratumumab Ready to Move to Front Line in Multiple Myeloma The first phase 3 trial in patients with newly diagnosed multiple myeloma found that daratumumab significantly improved progression-free survival when combined with triple therapy.