Sjögren's Syndrome News

• ACR 2020 Sjögren’s Symptom Clusters May Identify Treatment Options “Verification of features unique to each Sjögren’s cluster might provide guidance for future cluster-targeted therapy," said Sarah McCoy, MD, presenting at the American College of Rheumatology meeting.
  Medscape Medical News, November 13, 2020
• Combination Leflunomide-Hydroxychloroquine Promising for Sjogren's Syndrome A combination of two approved drugs, leflunomide and hydroxychloroquine, was safe and elicited a clinical response in a phase-2a trial for Sjogren's syndrome.
  Reuters Health Information, April 06, 2020
• Iscalimab Promising for Sjogren's Syndrome The anti-CD40 monoclonal antibody iscalimab showed preliminary efficacy against Sjogren's syndrome in a proof-of-concept study.
  Reuters Health Information, February 14, 2020
• ACR 2019 The Trick of Treating Cancer in Autoimmune Diseases For patients without a healthy immune system, immunotherapy could supercharge symptoms, but a new study is shedding light on how to go about treating cancer in patients with autoimmune diseases.
  Medscape Medical News, November 22, 2019
• Findings That Led to $183 Million Drug Development Deal Questioned Scientists tried to replicate some findings of a 'landmark' immunology study and were unable to do so.
  Medscape Medical News, July 31, 2019
• Early-Onset Sjögren's Linked to More Severe Disease Early-onset Sjogren's syndrome may be linked to more severe disease that worsens over time and has specific symptoms at presentation, a study found.
  Medscape Medical News, December 28, 2018
• Another AE Identified With Checkpoint Inhibitors Add connective tissue diseases, such as Sjogren's syndrome, to the list of immune-related adverse events that can develop during cancer treatment with immune checkpoint inhibitors.
  Medscape Medical News, February 28, 2017
• Cancer, Autoimmune Disorders Linked to Postsurgery GBS Malignancies and pre-existing autoimmune disorders were predictors of developing Guillain-Barré syndrome after a surgery or procedure in a new study.
  Medscape Medical News, November 29, 2016
• New Guidance on Managing Sjogren's Rheumatologic Problems Sjogren's Syndrome Foundation experts developed new guidelines on rheumatologic manifestations of the disease including fatigue, inflammatory musculoskeletal pain, and use of biologicals.
  Medscape Medical News, August 02, 2016
• Autoimmune Diseases Common in Patients With Vitiligo Patients with vitiligo commonly have other autoimmune diseases, according to a cross-sectional study.
  Reuters Health Information, November 18, 2015
• Pediatric Cancer Survivors at High Risk for Autoimmune Disease A population-based study has found that patients who survive cancer as children have an increased risk of developing autoimmune disease later in life.
  Medscape Medical News, November 11, 2015
• New Name, Diagnostic Criteria for Neuromyelitis Optica New diagnostic criteria have been introduced for neuromyelitis optica, which is now to be known as neuromyelitis optica spectrum disorder (NMOSD).
  Medscape Medical News, July 17, 2015
• Varying Tear Osmolarity Readings May Be Hard to Interpret Measurements of tear osmolarity taken with the TearLab Osmolarity System vary highly in individuals with and without dry eye, according to a new study.
  Reuters Health Information, April 02, 2015
• Sjogren's: Hydroxychloroquine No Better Than Placebo The commonly prescribed agent did not relieve symptoms of dryness, fatigue, or pain in a randomized controlled trial, but efficacy criteria may have been too tough, investigators say.
  Medscape Medical News, July 15, 2014
• EULAR Increased Cardiovascular Risk in Sjögren's Syndrome A population-based study suggests that heart attack and stroke should be considered direct complications of Sjögren's syndrome, not comorbidities.
  Medscape Medical News, June 14, 2014
• Ultrasound Improves Sjogren's Syndrome Classification Salivary gland ultrasonography enhances ACR classification of patients with Sjogren's syndrome and in the future should be included in evaluations, according to French investigators.
  Reuters Health Information, May 02, 2014
• Support for Autoimmune-Epilepsy Link A new population-based study provides more evidence of a significantly increased risk for epilepsy among patients with an autoimmune disease.
  Medscape Medical News, April 07, 2014
• Rituximab Disappoints in Sjogren Syndrome
  Medscape Medical News, February 18, 2014
• Autoantibodies May Precede Sjogren's Symptoms by Years Patients who develop Sjogren's syndrome may have autoantibodies characteristic of the disease in their blood years before any symptoms present, Swedish researchers say.
  Reuters Health Information, November 05, 2013
• Rituximab in Primary Sjogren's Syndrome A single course of rituximab affords only modest clinical benefit to patients with primary Sj�gren's syndrome, according to a small study from the Autoimmunity Centers of Excellence.
  Reuters Health Information, February 01, 2013