Sepsis News

• Newborn-Specific Antibiotic-Stewardship Programs Falling Short Few newborn-specific antibiotic-stewardship programs (ASPs) fully adhere to the Centers for Disease Control and Prevention (CDC) Core Elements of Hospital ASPs, according to an audit released today.
  Reuters Health Information, November 2018
• Some Infants at High Risk of Meningitis May Be Missed Without Lumbar Puncture Feverish young infants discharged from an emergency department (ED) without cerebrospinal fluid (CSF) testing may be at risk for meningitis and should be followed closely, researchers say.
  Reuters Health Information, November 2018
• Patient Selection Key in Nonoperative Appendicitis Care A new study finds that nonoperative management of patients with uncomplicated appendicitis can be successful, but the risk for complications and recurrence should be considered.
  Medscape Medical News, November 2018
• Gut Microbiome May Seed Sepsis A new bioinformatics tool, StrainSifter, points to the gut microbiome as a possible source of hospital-acquired bloodstream infections.
  Medscape Medical News, November 2018
• Prophylactic Antibiotics Ineffective Against Bloodstream Infections in ICUs In ventilated intensive care unit (ICU) patients, neither chlorhexidine (CHX) mouthwash nor selective oropharyngeal decontamination (SOD) nor selective digestive tract decontamination (SDD) seems to significantly reduce multidrug-resistant gram-negative bacteria (MDRGNB)-induced bloodstream infections in settings with moderate to high antibiotic resistance, researchers say.
  Reuters Health Information, October 2018
• Myo-Inositol Doesn't Prevent Severe Retinopathy of Prematurity Myo-inositol does not reduce the risk of type 1 retinopathy of prematurity (ROP) in infants born before 28 weeks' gestational age, according to new findings.
  Reuters Health Information, October 2018
• Hospitalization Linked to Dementia-Related Brain Changes Hospitalization, critical illness, and major infection may all be independent risk factors for altered brain structures commonly associated with Alzheimer's disease, new imaging research suggests.
  Medscape Medical News, October 2018
• Calorie-Dense Feedings Fail to Benefit ICU Patients on Ventilators Increasing the calorie density of enteral nutrition by 50% offers no 90-day survival benefit for critically-ill patients undergoing mechanical ventilation, according to a new study done in 46 intensive care units in Australia and New Zealand.
  Reuters Health Information, October 2018
• Shortened IV Antibiotic Course Works for Uncomplicated Group B Strep A shorter course of intravenous antibiotics was safe and effective for infants with uncomplicated, late-onset group B Streptococcus (GBS), in a retrospective study.
  Reuters Health Information, October 2018
• Early Dialysis Not Better for Septic Shock Patients With Acute Kidney Injury Early renal-replacement therapy for patients in the initial phase of septic shock who have severe acute kidney injury is no better than delayed therapy, according to a French study of 488 patients that was stopped early for futility.
  Reuters Health Information, October 2018
• IDWeekTop 5 New Antibiotics Advance to Fight Resistant Infections Five that are reaching the final trial stages and that target some of the most drug-resistant and deadly infections were spotlighted during a pipeline session at IDWeek.
  Medscape Medical News, October 2018
• IDWeekNew Antibiotics, Emerging Disease Threats Ahead at IDWeek Five antibiotics in the pipeline for some of the most resistant bugs, one of which is a phage therapy, will be in the spotlight at the upcoming IDWeek meeting.
  Medscape Medical News, September 2018
• Alternative Antibiotics After C-Section Linked to More Infections Women given alternatives to first-line cephalosporins showed a higher risk of surgical site infections, abscess, cellulitis, and other adverse outcomes.
  Medscape Medical News, September 2018
• Maternal Obesity Alone May Increase Neonatal Risks 'Obesity may be as important, if not more important, than hypertension and diabetes as a potentially modifiable risk factor for clinicians to target to improve neonatal outcomes,' new research hints.
  Medscape Medical News, September 2018
• A Child Dies Every Five Seconds, and Most Are Preventable Deaths - U.N. An estimated 6.3 million children died before their 15th birthdays in 2017, or one every five seconds, mostly due to a lack of water, sanitation, nutrition and basic healthcare, according to report by United Nations agencies on Tuesday.
  Reuters Health Information, September 2018
• Drug Combo No Better for Hard-to-Treat Bloodstream Infections A carbapenem-sparing option for the treatment of ceftriaxone-resistant infections was not equal to meropenem and should not be used in the setting of E coli or K pneumonia bloodstream infections.
  Medscape Medical News, September 2018
• Prostate Cancer Screening: No Effect on Overall Mortality Screening for prostate cancer may result in a small absolute benefit in disease-specific mortality over 10 years but does not improve overall mortality.
  Medscape Medical News, September 2018
• Fewer Deaths After Sepsis Protocol Mandate Fewer sepsis deaths occurred after implementation of state-mandated sepsis care bundles and reporting on sepsis care and patient outcomes, a study found.
  Medscape Medical News, September 2018
• Severe Delivery Complications Rising Among U.S. Pregnant Women An increasing proportion of U.S. women are experiencing serious and potentially life-threatening complications while giving birth, government researchers report.
  Reuters Health Information, September 2018
• Post-Hospital Interventions "Urgently Needed" for Children in Tanzania Post-hospital mortality is disturbingly high among two-to-12-year olds in Tanzania, and interventions are urgently needed, especially for older children with chronic illnesses, researchers say.
  Reuters Health Information, September 2018