Systemic Lupus Erythematosus News

• CMR May Detect Silent Heart Disease in New-Onset SLE CMR detected subclinical cardiac disease in patients with new-onset lupus, enabling earlier treatment, a study found; larger studies are needed to assess prognosis of earlier detection.
  Medscape Medical News, August 2018
• Delayed Adverse Skin Effects After PD-1-Inhibitor Therapy Eczema, psoriasis, and lupuslike reactions can occur even months after starting or stopping these drugs, so patients need to be monitored on an ongoing basis.
  Medscape Medical News, July 2018
• Drug Combination Boosts Older Adults' Immunity in Early Trial A phase 2a randomized, placebo-controlled clinical trial showed that a combination of drugs decreases the incidence of infections, including influenza and pneumonia, in older adults.
  Medscape Medical News, July 2018
• Physician Groups: Court Ruling May Harm Vulnerable Patients The Department of Justice recently lent unexpected support to a group of Republican attorneys general who are challenging the constitutionality of the Affordable Care Act in federal court.
  Medscape Medical News, June 2018
• Lilly's Lupus Treatment Succeeds in Mid-Stage Trial Eli Lilly & Co said its drug to treat autoimmune disease lupus met the main goal of a mid-stage trial, positioning the drugmaker to begin a bigger study later this year.
  Reuters Health Information, June 2018
• EULAR 2018New Osteoarthritis Treatments Garnering Attention at EULAR Interest in osteoarthritis is growing as new treatment options emerge, and insights will be discussed at the upcoming European League Against Rheumatism Congress (EULAR).
  Medscape Medical News, June 2018
• Subcutaneous Belimumab Improves Systemic Lupus Erythematosus Outcomes
  Reuters Health Information, April 2018
• Germany's Merck Seeks Partners for Cancer and Immune System Drugs Merck KGaA will seek development partners for experimental treatments including tepotinib as the German company looks to licensing deals to help fund clinical trials, according to its head of drug R&D.
  Reuters Health Information, April 2018
• Epstein-Barr Virus Transcription Factor Implicated in Seven Autoimmune Diseases
  Reuters Health Information, April 2018
• Patient Advocacy Groups Take in Millions From Drugmakers. Is There Payback? Kaiser Health News launches 'Pre$cription for Power,' a groundbreaking database to expose Big Pharma’s ties to patient groups.
  Kaiser Health News, April 2018
• ENDO 2018Adult-Onset Type 1 Diabetes, Other Autoimmune Diseases Linked The risk of developing additional autoimmune conditions rises with age of type 1 diabetes onset.
  Medscape Medical News, March 2018
• Biologics in Pregnancy Safe, Pose No Preterm or SGA Risk Previous studies finding a link between biologics exposure and preterm birth or SGA did not adequately account for potential confounders, researchers note.
  Medscape Medical News, March 2018
• Off-label Lenalidomide Might Be Alternative to Thalidomide for Erythema Multiforme Lenalidomide might be considered as off-label treatment for chronic erythema multiforme (EM) if the adverse effects of thalidomide are not acceptable, according to French researchers.
  Reuters Health Information, March 2018
• Synovial Analysis Identifies Distinct Rheumatoid Arthritis Subtypes Synovial gene expression and histology can be used to divide rheumatoid arthritis (RA) into high, low, and mixed inflammatory subtypes, according to results from the Accelerating Medicine Partnership: RA/SLE Network.
  Reuters Health Information, March 2018
• AstraZeneca Spins Off Autoimmune Drugs Into New Biotech Company AstraZeneca is spinning off six early-stage experimental drugs into a new $250 million standalone biotech company focused on severe autoimmune diseases.
  Reuters Health Information, February 2018
• Doctors Learn How to Talk to Patients About Dying Clinicians can be so focused on fixing problems and saving lives that they often avoid talking to patients about their prognosis.
  Kaiser Health News, February 2018
• Cancer Immunotherapy May Be Safe for Rheumatology Patients A minority of those who received immune checkpoint inhibitors and had underlying rheumatologic disease experienced flare-ups or adverse effects, a small study found.
  Medscape Medical News, January 2018
• Rheumatoid Arthritis May Confer Higher Cardiac and Infection Risks Patients with rheumatoid arthritis (RA) are at increased risk of serious infections, myocardial infarction (MI), and coronary heart disease (CHD), an analysis of Medicare claims data suggests.
  Reuters Health Information, January 2018
• Alert Self-injectable Belimumab for SLE Approved in Europe With training, patients with SLE can administer the new subcutaneous formulation as a once-weekly injection from a single-dose prefilled syringe or from a single-dose autoinjector.
  International Approvals, November 2017
• ACRNew ACR, EULAR Criteria Distinguish Lupus From Imitators Researchers from around the world contributed to the development of classification criteria for systemic lupus erythematosus (SLE) designed to distinguish the autoimmunity from common mimickers.
  Medscape Medical News, November 2017