Antiretroviral Therapy News

• AIDS 2020Injection Beats Pill for Long-Lasting HIV Prevention A long-lasting option for pre-exposure prophylaxis looks promising for people who have an issue with a daily pill, but some experts are urging the company to delay its application for approval.
  Medscape Medical News, July 09, 2020
• AIDS 2020'Time to Lay to Rest' Fears About Dolutegravir Birth Defects Rates of neural tube defects in newborns thought to be linked to the use of dolutegravir at the time of conception are much lower than previously reported, new data show.
  Medscape Medical News, July 08, 2020
• AIDS 2020Brazilian Patient in HIV Remission, Negative Antibody Test A 35-year-old man is in remission after receiving an intensified regimen of antiretroviral therapy plus nicotinamide supplementation. The results are being met with surprise, skepticism, and hope.
  Medscape Medical News, July 07, 2020
• AIDS 2020COVID-19 Disruptions 'Life Threatening' for People With HIV The COVID-19 pandemic has disrupted healthcare for people with all conditions. For people with HIV, the threat to health is just starting to come into focus.
  Medscape Medical News, July 06, 2020
• HIV Does Not Appear to Worsen COVID-19 Outcomes Most reports show that the risk for death from COVID-19 is no higher in people living with HIV than in those who are not, which means that standard social-distancing measures should be sufficient.
  Medscape Medical News, July 02, 2020
• Systemic Empirical TB Therapy No Better Than Targeted Treatment in HIV Patients The strategy of routinely treating newly diagnosed HIV patients with drugs to quell tuberculosis, even if the person has no signs or symptoms of TB, is not as effective as treatment based on TB testing, according to a large international study.
  Reuters Health Information, June 17, 2020
• GSK's Long-Acting Injection Beats Truvada in HIV Prevention Trial GSK said an injection every other month of its cabotegravir drug was shown to avert an HIV infection more effectively than Gilead's daily Truvada pill.
  Reuters Health Information, May 18, 2020
• HIV Preexposure Prophylaxis Underused by US Adolescents Greater education and attention are needed to address the underuse of HIV preexposure prophylaxis (PrEP) by US adolescents, according to a review.
  Reuters Health Information, May 11, 2020
• Drug-Drug Interactions Could Imperil COVID-19 Treatment A new tool identifies many common drugs that may cause harm when combined with experimental treatments for COVID-19.
  Undark, May 10, 2020
• Nothing Special About COVID-19 Manifestations in People With HIV The clinical characteristics of COVID-19 in patients with HIV appear to be similar to those without HIV, according to a small case series from Spain.
  Reuters Health Information, April 21, 2020
• Remdesivir Fits Binding Site in SARS-CoV-2 Enzyme The antiviral drug remdesivir binds to a newly identified section of a SARS-CoV-2 enzyme that is part of the virus' replication and transcription machinery, according to a structural analysis.
  Reuters Health Information, April 20, 2020
• New Test Accurately Detects Drug-Resistance Mutations in HIV-1 A new, near-point-of-care test detects drug-resistance mutations in HIV-1 with greater than 90% accuracy across mutant frequency thresholds, according to a validation study in Mexico.
  Reuters Health Information, April 08, 2020
• Intensified Drug Regimen May Prevent Intrapartum HIV Transmission After Late CART Start Perinatal antiretroviral intensification may prevent intrapartum transmission of HIV in women who start combination antiretroviral therapy (cART) late in pregnancy, new research suggests.
  Reuters Health Information, April 03, 2020
• Oral Anticoagulants Often Inappropriately Prescribed for HIV Patients on ART Direct oral anticoagulants (DOACs) are frequently prescribed for individuals on antiretroviral boosters, despite the risk of drug-drug interactions, researchers say.
  Reuters Health Information, April 01, 2020
• Dolutegravir May Carry Small Risk of Hyperglycemia in Patients With HIV Starting dolutegravir therapy in patients with HIV is associated with a small but significantly increased risk of severe, symptomatic hyperglycemia, researchers in Uganda report.
  Reuters Health Information, March 30, 2020
• Pharmacies Set Policies to Stop U.S. Hoarding of Potential Coronavirus Treatments Pharmacies CVS Health and Express Scripts, part of Cigna Corp, are setting up measures to prevent hoarding in the United States of malaria drug hydroxychloroquine and other treatments that are being tried against the new coronavirus.
  Reuters Health Information, March 25, 2020
• Mylan Waives Exclusive U.S. Distribution Rights for Potential COVID-19 Therapy U.S. drugmaker Mylan NV said on Wednesday it had waived its exclusive U.S. distribution rights to its generic version of HIV treatment Kaletra, which is currently being tested against the coronavirus.
  Reuters Health Information, March 25, 2020
• HIV Drug Combo Fails as Treatment for Severe COVID-19 in China Study
  Reuters Health Information, March 19, 2020
• Israel OKs Use of Generic Abbott Drug to Treat Coronavirus Despite Patent
  Reuters Health Information, March 19, 2020
• Johnson & Johnson Says No Evidence HIV Drug Works Against Coronavirus Johnson & Johnson said on Monday said on Monday there is no evidence its HIV drug, Prezista, had any effect against the coronavirus, in response to reports that the drug could inhibit the virus.
  Reuters Health Information, March 16, 2020
• Early ART Reduces Potential HIV Reservoir Antiretroviral therapy (ART) early in the course of acute HIV infection markedly reduces blood and tissue levels, researchers report.
  Reuters Health Information, March 12, 2020