Non-Hodgkin's Lymphoma News

• 'Landmark' Study Revises Molecular Classification of DLBCL Researchers uncover four genetic subtypes of diffuse large B-cell lymphoma with striking differences in 5-year overall survival, providing a potential path toward precision medicine treatment strategies.
  Medscape Medical News, April 2018
• AACR 2018Successful CAR T-Cell Tx Needs Good T Cells to Begin With Starting with poor-quality T cells may be a key problem in the manufacturing of effective and functional CAR T cells, which may explain why it has been difficult to apply this approach to all cancers.
  Medscape Medical News, March 2018
• FDA Panel Gives Nod to New Blincyto Use in ALL Blinatumomab would become the first treatment for which minimal residual disease positivity would be a selection criterion and MRD negativity an endpoint for acute lymphoblastic leukemia.
  Medscape Medical News, March 2018
• ECCOIBD Raises Gastrointestinal Cancer Risk Immunomodulators can intensify cancer risk in patients with bowel disease, despite their control of the underlying inflammation, and new information is emerging on the role of biologics.
  Medscape Medical News, February 2018
• CSSNo Follow-up in More Than a Third of AYA Cancer Survivors A large proportion of adolescent and young adult (AYA) cancer survivors are not receiving follow-up care after the end of their active treatment.
  Medscape Medical News, February 2018
• Young People Often Face Delays in Cancer Diagnosis Adolescents and young adults may have long delays between the onset of cancer symptoms and being diagnosed, according to data from the UK.
  Reuters Health Information, February 2018
• New CAR T Cell for Adult ALL, 'Game Changer' in Pediatric ALL A new CAR T cell has shown efficacy in adults with acute lymphoblastic leukemia (ALL), as the first of these products is hailed as a 'game changer' in pediatric ALL.
  Medscape Medical News, February 2018
• Clinical Cancer Advance of the Year Is CAR T Cells In its annual review of clinical cancer advances, the American Society of Clinical Oncology highlights CAR T cells as having 'historical significance.'
  Medscape Medical News, January 2018
• Breast Implants Tied to Increased Risk of Rare Blood Cancer Women who get breast implants may be more likely to develop anaplastic large-cell lymphoma, a small Dutch study suggests.
  Reuters Health Information, January 2018
• Call for 'Swift Action' on Blood Cancer Care in UK The earlier diagnosis of blood cancer requires greater awareness of the disease and the use of simple blood tests, say UK legislators, who call for greater integrated care and better patient support.
  Medscape Medical News, January 2018
• After Lymphoma, Risk for Breast Cancer Differs by Subtype The risk of developing estrogen-receptor-negative breast cancer following Hodgkin's lymphoma is increased regardless of prior radiotherapy.
  Medscape Medical News, January 2018
• Skin Exam Advised Before Anti-TNF-alpha Therapy Using tumor necrosis factor alpha (TNF-alpha) inhibitors for atypical dermatoses may unmask, or perhaps even worsen, cutaneous lymphoma, according to new research.
  Reuters Health Information, January 2018
• Few Patients Get CAR T Cells Because of 'Insurance Snags' Reimbursement problems related to the very high cost of therapy are causing delays in patients' receiving CAR T-cell therapy. Several experts relate their experiences.
  Medscape Medical News, January 2018
• ASHCAR T Cells: Exciting, but Who Is Going to Cover Costs? An analysis of Medicare reimbursement shows that even with a 400% markup, hospitals will be hit with a financial loss.
  Medscape Medical News, December 2017
• Physical Activity Helps Lymphoma Patients Live Longer For lymphoma patients, increasing physical activity lowers the risk of death from any cause and from lymphoma, according to results of an observational study.
  Reuters Health Information, December 2017
• ASHFirst in 30 Years: Improved Front Line in Hodgkin's Lymphoma Brentuximab vedotin has already made an impact on the management of relapsed/refractory classical Hodgkin's lymphoma. Now the drug is poised for frontline use.
  Medscape Medical News, December 2017
• ASHCAR T Cells in Advanced R/R Lymphoma: Keeping Patients Alive New longer-term data on CAR T cells in patients with refractory and relapsed (R/R) lymphoma show that responses are durable, with about half of patients alive after a year or more.
  Medscape Medical News, December 2017
• ASHMogamulizumab: Valuable New Option for Cutaneous Lymphoma An investigational monoclonal antibody directed against chemokine receptor 4 significantly improved progression-free survival in patients with cutaneous T-cell lymphoma.
  Medscape Medical News, December 2017
• ASHQuestion Relevant to All Oncologists Answered at ASH 2017 Cancer patients are at higher risk for venous thromboembolism. To date, the standard treatment has been subcutaneous low-molecular-weight heparin products, but now there are data on newer oral agents.
  Medscape Medical News, November 2017
• Anti-TNF Agents, Thiopurines Increase Lymphoma Risk in IBD Thiopurines and anti-TNF agents were associated with a small but significant increase in the risk for lymphoma in patients with IBD, particularly when used in combination, a study has found.
  Medscape Medical News, November 2017