Bladder Cancer News

• Don't Remove Bladder for Localized Muscle-Invasive Cancer Investigators say bladder-preserving treatment should be offered to all patients, not just poor surgical candidates.
  Medscape Medical News, May 26, 2023
• FDA Declines to Approve Bladder Cancer Therapy ImmunityBio said on Thursday the FDA has declined to approve its combination therapy to treat a type of bladder cancer due to deficiencies in the company's application.
  Reuters Health Information, May 11, 2023
• GSK Loses Bid to Keep Experts Out of Upcoming Zantac Trial A California judge on Thursday denied GSK's bid to keep expert testimony linking its discontinued heartburn drug Zantac to cancer out of an upcoming trial, a setback for the British drugmaker.
  Reuters Health Information, March 24, 2023
• For Which Indications Is Penile Rehabilitation Appropriate? A urologist and andrologist recently reviewed the situations in which penile rehabilitation is indicated for the prevention of chronic erectile dysfunction.
  Medscape Medical News, March 20, 2023
• EAU 2023 Trial Casts Shadow on Photodynamic Surgery for Bladder Cancer Photodynamic diagnosis-guided TURBT did not reduce 3-year recurrence rates of non–muscle-invasive bladder cancer in a real-world trial compared with white light-guided cystoscopy.
  Medscape Medical News, March 15, 2023
• EAU 2023 Urine Test Predicts Future Bladder Cancer 12 Years Before Symptoms A 10-gene assay predicted future cases of urothelial cancer, the most common form of bladder cancer, with a high degree of sensitivity and specificity.
  Medscape Medical News, March 13, 2023
• Gemcitabine-Docetaxel Effective Alternative to BCG in NMIBC The chemotherapy duo performed better than expected as a stand-in for bacillus Calmette-Guérin (BCG), which is the gold standard for non–muscle-invasive bladder cancer but is currently in short supply.
  Medscape Medical News, March 07, 2023
• Antibiotics in Previous Year Reduce ICI Effectiveness After finding that immune checkpoint inhibitors (ICIs) do not work as well for patients who had taken antibiotics, the investigators suggest restoring the gut microbiome before starting therapy.
  Medscape Medical News, March 07, 2023
• First Zantac Cancer Risk Trial in California Postponed by Months The first scheduled trial over claims that GSK's heartburn drug Zantac caused cancer, which had been set to begin Monday, has been postponed, likely by several months.
  Reuters Health Information, February 27, 2023
• GUCS 2023 Pembrolizumab Activity in BCG-Refractory Papillary Bladder Cancer Pembrolizumab monotherapy showed promising antitumor activity for patients with high-risk non–muscle invasive bladder cancer that did not respond to standard treatment with BCG.
  Medscape Medical News, February 27, 2023
• GUCS 2023 Adjuvant Nivolumab as Standard of Care in Resected Bladder Cancer Extended follow-up from the CheckMate 274 trial further supports adjuvant nivolumab as a standard of care for patients with resected muscle-invasive urothelial carcinoma.
  Medscape Medical News, February 20, 2023
• Judge Weighs Key Evidence Ahead of First Zantac Cancer Trial Lawyers for a man who alleges he developed bladder cancer after taking heartburn drug Zantac urged a California judge on Thursday to allow expert testimony at an upcoming trial.
  Reuters Health Information, February 17, 2023
• Diabetes Drug Tied to Lower Dementia Risk New research supports the potential cognitive benefit of pioglitazone, particularly in the setting of high ischemic burden, suggesting a possible personalized avenue to treatment.
  Medscape Medical News, February 16, 2023
• New Trials in Urologic Cancers: Could Your Patient Benefit? Perhaps one of your patients could benefit from clinical trials that are currently recruiting patients with urologic cancers, including prostate cancer.
  Medscape Medical News, February 06, 2023
• COPD Patients at Higher Risk of Death 1 Year After Surgery Patients with chronic obstructive pulmonary disease are 26% more likely to die after elective surgery and to incur increased healthcare costs, compared with peers without the condition, researchers say.
  Medscape Medical News, January 18, 2023
• Alert FDA Approves First Gene Therapy for Bladder Cancer A clinical trial found that half of participants had a complete response to nadofaragene firadenovec (Adstiladrin).
  Medscape Medical News, December 16, 2022
• Alert Atezolizumab Bladder Cancer Indication Withdrawn in US The manufacturer has voluntarily withdrawn the US indication that covered its use in certain patients with bladder and urinary tract cancers.
  Medscape Medical News, November 29, 2022
• Alert FDA Approves New Immunotherapy Combo for Liver Cancer The new combination includes a priming dose of the CTLA-4 antibody tremelimumab, which is approved for the first time worldwide.
  FDA Approvals, October 24, 2022
• ACG 2022 Circulating Tumor DNA Test May Help Guide GI Cancer Management A ctDNA test may be sensitive enough to assess tumor burden and help guide treatment plans for people with locally advanced or metastatic colorectal cancer.
  Medscape Medical News, October 23, 2022
• Renowned Oncologist Nicholas Vogelzang, MD, Dies at 72 Vogelzang left his mark as a medical oncologist and cancer investigator, helping shepherd a handful of cancer drugs through clinical trials.
  Medscape Medical News, September 27, 2022