Marshall on Oncology

 
 
  • Is Adjuvant Chemo Needed in Rectal Cancer?   Dr. John Marshall asks, 'Why are we giving patients oxaliplatin when our evidence doesn't demonstrate much, if any, benefit?
  • Taking the Boards: A Frisking, Then a Mugging   Dr. John Marshall found board certification 'really hard,' partly because questions had no right answer. He asks: Are boards a fair measure of a practicing physician's skills and knowledge base?
  • Caution! Anti-EGFR Therapy May Endanger mCRC Patients   Dr. John Marshall reports that in patients with metastatic colorectal cancer, anti-EGFR therapy could not only prove ineffective but actually harmful, depending on their RAS mutations.
  • Dazed and Confused About Molecular Data?   Is molecular profiling integral to choice of treatment or simply a source of confusion? Dr. John Marshall speaks to issues that need to be resolved before 'personalized medicine' is practice-ready.
  • Who's in It for the Cure?   Dr. John Marshall takes to his electronic chalkboard to tackle the problem of coordinating the separate agendas of cancer stakeholders, and finds a simple yet elegant solution.
  • A C-change in Adjuvant Pancreas Cancer?   Dr. John Marshall reports on progress in treatment of metastatic pancreas cancer using traditional drugs, and questions current use of adjuvant capecitabine on the basis of a recent study from Japan.
  • Least Is Best in CRC Follow-up   Drs. David Kerr and John Marshall discuss colorectal cancer highlights from ASCO, including findings on follow-up scans, chemo holidays, and drug combos.
  • 'GI Gang' Goes in for Refinements   Dr. John Marshall previews important topics to be addressed in the GI poster sessions at ASCO, including front-line and maintenance therapies for CRC, and adds a personal wish.
  • Get a Dog and Start Walking   Modest exercise can improve survival in patients with colorectal cancer at a rate superior to that for adjuvant therapy, says Dr. John Marshall. Time to tell patients to lace up their sneakers.
  • Could Practice Changes Send Oncologists to the Hospital?   Dr. John Marshall cites 2 trends that put an increased burden on practicing oncologists, especially those in small practices. Will these changes send oncologists from private practice to the hospital?
  • Why Are Only 3% of US Cancer Patients in Clinical Trials?   If clinical trials fuel oncology breakthroughs, is US research running on vapors? Dr. John Marshall talks about steps to meet stakeholders' priorities and improve patient recruitment.
  • Good for Celebrants, Better for Colon Cancer Patients   Dr. John Marshall discusses a study that found regular aspirin use to increase survival in CRC patients, especially those with PIK3CA mutation. But should all CRC patients take it, and at what dose?
  • Ready for the Storm of 40 Million Strong?   We knew when Hurricane Sandy would make landfall and got ready. A surge of 40 million new patients will probably enter the US healthcare system in 2014. Dr. John Marshall asks whether we're prepared.
  • Practice of Medicine: Anxiety Up, Morale Down   If healthcare as an industry is booming, asks Dr. John Marshall, then why is morale low among physicians? He has an idea or two -- and a question.
  • TV's 'House' Care Is Not Healthcare   Dr. John Marshall says that the boutique-level healthcare depicted on television in such dramas as House affects patients' ideas of hospital care, but a little management of expectations is in order.
  • Aflibercept Offers New Option in CRC   Dr. John Marshall reviews the mechanism of action, survival improvement, and side effects of aflibercept as second-line therapy in metastatic colon cancer.
  • Four Key Pieces in the Healthcare Puzzle   Dr. John Marshall identifies 4 facets of the healthcare system that need retooling if sustainable healthcare is going to be possible in the United States.
  • Colorectal Cancer: New Drugs, Emerging Paradigms   Dr. John Marshall highlights colorectal studies on aflibercept, regorafenib, maintenance therapy, perioperative chemotherapy, and second-line therapy, to be presented at ASCO® 2012.
  • Cleaning the Healthcare Closet   Because the healthcare budget is not likely to get any bigger, Dr. John Marshall comments that we may need to 'clean the healthcare closet' to make room for new therapies. What can we do without?
  • EMR: Efficiency Mauled Repeatedly   Dr. John Marshall says that his efficiency as a clinician is undermined as he spends more and more time entering data into the EMR with less and less administrative support. Is there a way out?