Journal of Medical Case Reports

 
 

Journal of Medical Case Reports (JMCR) is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. All articles are indexed in PubMed and archived in PubMed Central, and all articles are openly accessible and available for reuse under the Creative Commons Attribution License. See: http://www.biomedcentral.com/info/about/license.

  • Juvenile Huntington's Disease In a small number of cases, Huntington's disease manifests prior to age 21. This case report highlights the complexity of juvenile Huntington's and how its course differs from adult onset disease.
  • Pericardial Effusion, Cardiac Tamponade in a COVID-19 Patient This case report documents acute pericarditis, pericardial effusion, and cardiac tamponade as a possible presentation of COVID-19.
  • Recovery From COVID-19 and ARDS This case report of a patient who developed ARDS due to COVID-19 highlights the importance of ICU follow-up visits with comprehensive physical and cognitive testing following acute hospitalization.
  • Pancreatic Ascites Managed With a Conservative Approach This case of massive ascites in a patient with chronic pancreatitis secondary to chronic alcohol use was successfully managed with a combination of medical and interventional therapy.
  • Cannabinoids in a Pediatric Patient With Autism and Epilepsy A very low dose of cannabidiol-based extract produced positive effects on behavioral symptoms and core social deficits in this young patient with autism spectrum disorder, anxiety, and epilepsy.
  • Hilar Lymphadenopathy in the Setting of COVID-19 This report illustrates the possibility of hilar lymphadenopathy as an uncommon clinical and radiological finding in the setting of COVID-19.
  • Long-term Follow Up After Denosumab Treatment for Osteoporosis This report highlights the potential for rebound effect with strong bone hyper-reabsorption in certain patients after stopping treatment with denosumab.
  • Adrenal Insufficiency in Coronavirus Disease 2019 This case of a COVID-19 patient with vasopressor-resistant hypotension highlights the need to be aware of acute adrenal insufficiency as a non-respiratory presentation of SARS-CoV-2 infection.
  • Disseminated Enterovirus Infection With Rituximab/Ibrutinib This case underscores the risk for severe and potentially life-threatening immune-related side effects with combined therapy with rituximab and ibrutinib.
  • Atezolizumab-associated Encephalitis in Metastatic Lung Cancer This case demonstrates encephalitis as an rare but potentially serious adverse event associated with the immune checkpoint inhibitor atezolizumab.
  • Refractory Pemphigus Vulgaris Responded to Plasmapheresis This case highlights the importance of plasmapheresis as a useful intervention in patients with pemphigus vulgaris who do not respond to conventional therapy.
  • DVT in Rheumatoid Arthritis Presenting as a Calf Strain This case report underscores the need to be aware of deep vein thrombosis as a potential risk in rheumatoid arthritis, even in young, physically fit individuals.
  • Dramatic Radiotherapy Response in a Necrotic Lymphoma Mass This case illustrates the potential for single modality palliative radiotherapy to reduce disease burden in patients with diffuse large B-cell lymphoma who are not fit for systemic therapy.
  • Flight of the COVID-19 Patient: Experience With a Wuhan Evacuee This case report documents the clinical course of one of the earliest cases of COVID-19 in the U.S., offering insight into the clinical and laboratory findings of this novel disease.
  • A 95-year-old Patient With Unexpected COVID-19 This case report of an initially misdiagnosed patient highlights the potential pitfalls in diagnosing COVID-19 pneumonia in very old patients with comorbidities.
  • Sporotrichosis in Renal Transplant Patients Review the presentation, diagnosis, and treatment of sporotrichosis, a rare opportunistic infection that occurs mostly in renal transplant patients.
  • Omeprazole- and Pantoprazole-induced Asymptomatic Hyponatremia This case highlights the need to be aware of the possibility of hyponatremia as an uncommon side effect of proton pump inhibitors.
  • Diffuse Large B Cell Lymphoma Masquerading as GCA This case illustrates an atypical presentation of diffuse large B cell lymphoma initially misdiagnosed as biopsy-negative giant cell arteritis. How was the correct diagnosis finally obtained?
  • HCV Relapse After Successful Treatment With DAAs HCV recurred in this patient 6 months after achieving SVR with direct-acting antiviral therapy, along with a sarcomatous change in HCC. What might be the relationship between these events?
  • Swelling of the Ear Lobe As a Manifestation of Lyme Disease This case describes an unusual dermatologic presentation of Lyme disease, borrelial lymphocytoma, which is rare in the US but more common in Europe.
  • An Adolescent Girl With Symptoms of Anaphylaxis This 14-year-old girl with a history of weight loss and food allergies presented with symptoms of anaphylaxis, but allergy and immunological workup were negative. What was the real etiology?
  • Venetoclax/carfilzomib/dexamethasone in Refractory MM Multiple myeloma remains difficult to treat with inevitable relapse in the majority of patients. This report documents treatment of two refractory patients with a novel therapeutic combination.
  • Rapid Cognitive Decline in a Patient With CLL This 68-year-old patient being treated with ofatumumab for chronic lymphocytic leukemia presented with progressive cognitive decline and neurological dysfunction. What was the cause?
  • Primary Neuroendocrine Tumors of the Breast Primary neuroendocrine tumors of the breast are rare, and diagnosis can be difficult. How is a definitive diagnosis obtained?
  • Metastatic Melanoma With Neuroendocrine Differentiation This case illustrates how the manifestation of a malignant melanoma with neuroendocrine features can mimic a neuroendocrine carcinoma. How was the correct diagnosis obtained?