Journal of Medical Case Reports

 
 

Journal of Medical Case Reports (JMCR) is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. All articles are indexed in PubMed and archived in PubMed Central, and all articles are openly accessible and available for reuse under the Creative Commons Attribution License. See: http://www.biomedcentral.com/info/about/license.

  • A 95-year-old Patient With Unexpected COVID-19 This case report of an initially misdiagnosed patient highlights the potential pitfalls in diagnosing COVID-19 pneumonia in very old patients with comorbidities.
  • Sporotrichosis in Renal Transplant Patients Review the presentation, diagnosis, and treatment of sporotrichosis, a rare opportunistic infection that occurs mostly in renal transplant patients.
  • Omeprazole- and Pantoprazole-induced Asymptomatic Hyponatremia This case highlights the need to be aware of the possibility of hyponatremia as an uncommon side effect of proton pump inhibitors.
  • Diffuse Large B Cell Lymphoma Masquerading as GCA This case illustrates an atypical presentation of diffuse large B cell lymphoma initially misdiagnosed as biopsy-negative giant cell arteritis. How was the correct diagnosis finally obtained?
  • HCV Relapse After Successful Treatment With DAAs HCV recurred in this patient 6 months after achieving SVR with direct-acting antiviral therapy, along with a sarcomatous change in HCC. What might be the relationship between these events?
  • Swelling of the Ear Lobe As a Manifestation of Lyme Disease This case describes an unusual dermatologic presentation of Lyme disease, borrelial lymphocytoma, which is rare in the US but more common in Europe.
  • An Adolescent Girl With Symptoms of Anaphylaxis This 14-year-old girl with a history of weight loss and food allergies presented with symptoms of anaphylaxis, but allergy and immunological workup were negative. What was the real etiology?
  • Venetoclax/carfilzomib/dexamethasone in Refractory MM Multiple myeloma remains difficult to treat with inevitable relapse in the majority of patients. This report documents treatment of two refractory patients with a novel therapeutic combination.
  • Rapid Cognitive Decline in a Patient With CLL This 68-year-old patient being treated with ofatumumab for chronic lymphocytic leukemia presented with progressive cognitive decline and neurological dysfunction. What was the cause?
  • Primary Neuroendocrine Tumors of the Breast Primary neuroendocrine tumors of the breast are rare, and diagnosis can be difficult. How is a definitive diagnosis obtained?
  • Metastatic Melanoma With Neuroendocrine Differentiation This case illustrates how the manifestation of a malignant melanoma with neuroendocrine features can mimic a neuroendocrine carcinoma. How was the correct diagnosis obtained?
  • Toxicity Due to Combination of Leflunomide and Methotrexate: Therapy with methotrexate and leflunomide in a patient with active rheumatoid arthritis produced an unusual combination of drug-induced thrombotic microangiopathy and liver injury.
  • Robotic Voluminous Paraesophageal Hernia Repair This review examined the safety and efficacy of a robotic approach to paraesophageal hernia repair. Is it a feasible alternative to standard laparoscopic repair?
  • Multiple Electrolyte Imbalances: A Diagnostic Dilemma What was the mysterious etiology of this patient's multiple electrolyte abnormalities? This case underscores why lab findings should be given credence in cases where patient history may be unreliable.
  • Scurvy May Occur in Children With No Underlying Risk Factors This case highlights that while still rare, scurvy still exists in the pediatric population and may present even in otherwise healthy children with no apparent risk factors.
  • Coupled Blue and Red LED Therapy Efficacy for Rosacea This case series demonstrates how the use of photodynamic therapy, specifically via light-emitting diodes, can provide an effective, safe, and well-tolerated alternative treatment for acne rosacea.
  • AKI and Hepatitis Associated With Energy Drink Consumption This case highlights two potential and serious adverse effects associated with over-consumption of energy drinks.
  • Metformin-associated Lactic Acidosis Treated With Dialysis Lactic acidosis is a rare but potentially serious adverse effect of metformin therapy. Might continuous renal replacement therapy be advantageous in metformin-associated lactic acidosis?
  • Low-dose Diclofenac to Control Fever After Ischemic Stroke Central fever following ischemic stroke is fairly common and associated with worse outcomes. Might the NSAID diclofenac sodium be an effective antipyretic in this situation?
  • Neoadjuvant Imatinib for an Uncommon Breast Malignancy This case highlights the differentiation of dermatofibrosarcoma protuberans from metaplastic breast carcinoma and other spindle cell lesions, as well as the use of imatinib as neoadjuvant treatment.
  • Gallbladder Hemorrhage During Oral Edoxaban Therapy This case suggests that gallbladder hemorrhage needs to be considered as a possible complication for patients on direct oral anticoagulants.
  • rt-PA in Ischemic Stroke After Idarucizumab Administration This case demonstrates that thrombolytic therapy with rt-PA after reversal of dabigatran with idarucizumab may be safe and feasible in patients with acute ischemic stroke with lacunar infarct.
  • Acute Inferior STEMI Due to Delirium Tremens Was this patient's ST-elevation myocardial infarction directly related to his severe alcohol withdrawal? What might be the underlying pathophysiology of such a relationship?
  • Levothyroxine-induced Liver Injury Drug-induced liver injury is rarely observed with levothyroxine therapy; this case demonstrates that it can be reversible with cessation of the drug.
  • Severe Thrombocytopenia in a Patient With Lung Adenocarcinoma This case of severe grade V thrombocytopenia caused by nivolumab highlights the need for clinicians to be aware of this potential adverse effect of immune-checkpoint inhibitors.