In Short

• Bulevirtide for Hep D: Phase 3 Data Now Published in NEJM Bulevirtide, an investigational, first-in-class hepatitis delta virus entry-inhibitor, significantly reduced viral load and normalized liver enzymes in patients.
  Medscape Medical News, July 07, 2023
• High-Dose Vitamin D May Cut Risk for New Atrial Fibrillation The risk fell by about a third over 4 years in nonvitamin D-deficient older adults who took vitamin D3 at 3200 IU daily, in a post hoc finding from a randomized trial.
  Medscape Medical News, July 05, 2023
• GLP-1 Agonists Help in Type 2 Diabetes With Liver Cirrhosis In adults with cirrhosis and type 2 diabetes, glucagon-like peptide-1 receptor agonist therapy significantly lowered the risk for death and other adverse outcomes, a study found.
  Medscape Medical News, June 30, 2023
• SSRI Improves Cognition, Major Depression in Early Dementia An open label study shows the antidepressant vortioxetine significantly improves depressive symptoms and cognition in patients with both major depressive disorder and early-stage dementia.
  Medscape Medical News, June 20, 2023
• Therapists' Oxytocin Levels Tied to Patient Outcomes Physiologic responses of therapists as measured by oxytocin levels may play a role in therapeutic outcomes in patients with depression.
  Medscape Medical News, June 19, 2023
• Methotrexate Does Not Impair Sperm Quality The findings provide reassurance that men can start methotrexate therapy while actively pursuing parenthood.
  Medscape Medical News, June 16, 2023
• Endovascular Aortic Repair Promising in CTD
  Medscape Medical News, June 16, 2023
• Herbal Combo Shows Promise in Active Ulcerative Colitis Curcumin plus Qing Dai was effective for inducing response and remission in patients with active ulcerative colitis in a small placebo-controlled trial.
  Medscape Medical News, June 15, 2023
• Low-Carb, Plant-Rich Diets Tied to Breast Cancer Survival? A low-carbohydrate diet, especially one rich in plant-based foods, was linked to better overall, but not breast cancer-specific, survival in women with stage I-III breast cancer.
  Medscape Medical News, June 15, 2023
• Eye Damage Affects 26% of Those With Diabetes in the US A study led by the CDC shows that 26% of US residents with diabetes had diabetic retinopathy and 5% had vision-threatening retinopathy in 2021.
  Medscape Medical News, June 15, 2023
• Teen Depression and Dyslipidemia: New Data Researchers believe early-onset major depressive disorder could provide a window of opportunity to mitigate increased cardiovascular disease risks associated with dyslipidemia.
  Medscape Medical News, June 14, 2023
• High-Dose Regimen Fixes Severe Obesity From Mutated Leptin Children making certain dysfunctional variant forms of leptin as a result of genetic mutations required a hugely increased dose of a leptin analog to achieve weight loss and other clinical responses.
  Medscape Medical News, June 14, 2023
• Frailty Linked to Lower Use of Guideline Treatments in HFrEF Study results suggest a gap between guideline-recommended medical therapy and prescription of drugs to frail patients with heart failure with reduced ejection fraction.
  Medscape Medical News, June 14, 2023
• Food Allergies Vary by Race, Income Researchers examined rates of common food allergies in a survey of more than 51,000 households.
  Medscape Medical News, June 14, 2023
• Crohn's Associated With HS in Kids, Analysis Suggests The low absolute prevalence of Crohn's disease among pediatric patients with hidradenitis suppurativa "is reassuring," the researchers write.
  Medscape Medical News, June 14, 2023
• Predicting Hypothyroid Onset in Adults With Kidney Disease Researchers derived and validated a prediction model for incident hypothyroidism in adults with stage 4-5 chronic kidney disease with an eGFR of less than 30 mL/min/1.73m2.
  Medscape Medical News, June 14, 2023
• Behavioral Techniques Help Kids With Obesity, Their Families Treatment involving a child's entire family was successfully adapted to a primary care setting.
  Medscape Medical News, June 13, 2023
• Genetic Counseling Enhances Patient Empowerment in fCRC Genetic counseling for patients with familial colorectal cancer provides significant improvement in feelings of empowerment and mental health, results of the first randomized controlled trial show.
  Medscape Medical News, June 13, 2023
• New Insight Into Drivers of Self-Harm in Teens Hypothalamic-pituitary-adrenal (HPA) axis dysregulation plays a central role in adolescents who engage in nonsuicidal self-injury behavior during times of stress, such as during the COVID-19 pandemic.
  Medscape Medical News, June 13, 2023
• Insurance Status Tied to Transfer for STEMI Uninsured patients with ST-segment elevation myocardial infarction who presented to the ED were less likely to be transferred to another facility than their insured counterparts, a cohort study suggests.
  Medscape Medical News, June 13, 2023