Alzheimer's Disease Center of Excellence: News and Perspective

• Poor Bone Health a 'Robust' Dementia Risk Factor Low bone density, particularly at the femoral neck, may raise dementia risk in older adults, possibly through the little-known bone-brain axis.
  Medscape Medical News, March 23, 2023
• Longer Telomeres Tied to Better Brain Health A new study shows an association between longer telomere length and healthier brain structures and lower risk for dementia in older adults.
  Medscape Medical News, March 22, 2023
• Restless Legs a New Modifiable Risk Factor for Dementia? Restless legs syndrome has been associated with an increased risk of dementia in new findings that suggest the disorder may be a risk factor for or an early noncognitive sign of dementia.
  Medscape Medical News, March 22, 2023
• Causal Link Found Between T2D and Dementia A Mendelian randomization study in more than 300,000 mostly male US veterans found that those with type 2 diabetes were more likely to develop dementia, vascular dementia, and Alzheimer's disease.
  First Look, March 21, 2023
• Bruce Willis' Dementia Is Not Your Grandpa's Dementia A neuroscientist reviews how FTD differs from more common forms of dementia with little initial impact on a patient's broader memory and associated cognitive abilities.
  Medscape Neurology, March 20, 2023
• Music Intervention Calms Agitation in Severe Dementia Listening to a personalized musical playlist has been linked to mitigation of behavioral and psychological disturbances in patients with severe dementia.
  Medscape Medical News, March 20, 2023
• Med Diet Guards Against Dementia, Regardless of Genetic Risk Higher adherence to the healthy Mediterranean diet was associated with lower dementia risk, independently of genetic risk in a large population study suggests.
  Medscape Medical News, March 14, 2023
• Two Diets Tied to Lower Alzheimer's Pathology at Autopsy A brain autopsy study shows less AD pathology with greater adherence to the MIND or Mediterranean diets.
  Medscape Medical News, March 09, 2023
• AAGP 2023 Antipsychotic Cuts Alzheimer's-Related Agitation The antipsychotic brexpiprazole effectively improves agitation associated with Alzheimer's disease with favorable tolerability, results of a phase 3 study suggest.
  Medscape Medical News, March 09, 2023
• Childhood Nightmares a Prelude to Cognitive Problems, PD? Persistent distressing dreams in childhood have been linked to a significantly increased risk for cognitive decline and Parkinson's disease later in life.
  Medscape Medical News, March 06, 2023
• Vitamin D a Viable Strategy for Dementia Prevention? New research suggests vitamin D supplementation may help ward off dementia, especially when initiated early, new research suggests.
  Medscape Medical News, March 06, 2023
• ACTRIMS 2023 Digital Tool a Better Disability Measure in MS? A digital tool to measure gait, which has been used in trials of Alzheimer's and Parkinson's disease, shows potential in improving measurement of disability among patients with multiple sclerosis.
  MDedge News, March 03, 2023
• Black People Less Likely to Receive Dementia Meds Black people are less likely than White patients to receive medications to manage dementia-related symptoms in the outpatient setting, in line with what’s been found in nursing homes and hospitals.
  Medscape Medical News, March 03, 2023
• ACTRIMS 2023 Physical Activity a Growing Priority for Patients With MS With mounting research showing that physical activity affects brain volume, fatigue, and other outcomes, researchers are finding ways to have patients with multiple sclerosis be more active.
  Medscape Medical News, March 03, 2023
• FDA Official Who Oversaw Aducanumab Approval Retiring An FDA official who oversaw the approval of the controversial Alzheimer's therapy aducanumab is retiring from the agency to 'explore other opportunities.'
  Medscape Medical News, March 03, 2023
• A Revolution in the Treatment Landscape of AD   Andrew N. Wilner, MD, and Richard J. Caselli, MD, discuss developments in the treatment of Alzheimer's disease.
  Medscape Neurology, March 02, 2023
• Epilepsy in Nursing Homes: The Need for Education   Andrew N. Wilner, MD, and Ilo E. Leppik, MD, discuss research presented at the American Epilepsy Society meeting.
  Medscape Neurology, March 01, 2023
• Middle-Aged Smokers Face Higher Risk for Dementia Middle-aged smokers are far more likely to report having memory loss and confusion than nonsmokers.
  Quick Take, February 27, 2023
• Higher Dementia Risk in Women Explained? Dementia risk is significantly higher in women than in men worldwide, and social and economic disadvantages among women could be to blame, a new study suggests.
  Medscape Medical News, February 24, 2023
• Regular Laxative Use Tied to Increased Dementia Risk Regular use of laxatives may increase the risk of dementia, especially among those who use multiple types of laxatives or osmotic laxatives, new research suggests.
  Medscape Medical News, February 24, 2023