Neurology News

• Antiamyloid Gantenerumab Disappoints in Phase 3 Trials The antiamyloid monoclonal antibody gantenerumab led to a lower amyloid plaque burden but no clear cognitive benefit in early Alzheimer's disease in twin pivotal trials.
  Medscape Medical News, November 21, 2023
• Choosing the Right Approach to Cancer and Menopause Symptoms Hormone replacement therapy may be considered to lessen these symptoms, but only in certain conditions, said a gynecologist.
  Medscape Medical News, November 21, 2023
• PREVENT: AHA's New Risk Calculator Incorporates CKM Health The new cardiovascular disease risk equations start at age 30, include measures of kidney and metabolic health, add heart failure, and remove race from the equations.
  Medscape Medical News, November 20, 2023
• Asundexian Phase 3 AF Study Halted for Lack of Efficacy The phase 3 OCEANIC-AF trial of the factor XI inhibitor asundexian (Bayer) has been stopped early owing to inferior efficacy vs apixaban in preventing stroke and systemic embolism in patients with AF.
  Medscape Medical News, November 20, 2023
• Alert FDA OKs Symplicity Renal Denervation System for Hypertension After a mixed FDA panel review in August, the agency has approved Medtronic's Symplicity Spyral renal denervation system for treatment of hypertension.
  Medscape Medical News, November 20, 2023
• Alert FDA Expands Enzalutamide Approval to Earlier Prostate Cancer The expanded approval makes enzalutamide the first and only approved androgen receptor signaling inhibitor in the nonmetastatic castration-sensitive prostate cancer setting.
  Medscape Medical News, November 17, 2023
• Before Signing an Offer Letter: Read This You just received an offer letter, but should you sign it right away? How legally binding is it? Is it the same as a contract? Experts weigh in.
  Medscape Medical News, November 17, 2023
• Tool May Help Boost Confidence in Ability to Recall Memories A new intervention tool is training older adults to boost their everyday memory.
  Medscape Medical News, November 17, 2023
• Alert FDA OKs First-Line Pembro With Chemo for Gastric/GEJ Cancer Adding pembrolizumab to chemotherapy had significant benefits in patients with locally advanced unresectable or metastatic, HER2-negative gastric or gastroesophageal junction adenocarcinoma.
  Medscape Medical News, November 17, 2023
• Alert FDA OKs Capivasertib for Certain Advanced Breast Cancers The first-in-class AKT inhibitor administered with fulvestrant prolonged PFS vs fulvestrant alone in patients with PIK3CA/AKT1/PTEN-altered tumors.
  Medscape Medical News, November 17, 2023
• Hourly Air Pollution Exposure: A Risk Factor for Stroke Daily exposure to air pollutants has been linked to stroke. A new study investigates the link between hourly exposure to air pollutants and emergency stroke admission shortly after exposure.
  Medscape Medical News, November 17, 2023
• Women Stroke Survivors Fear Disparity in Emergency Care Women with a history of stroke voice their experiences with emergency care, reflecting the challenges they face and the urgent necessity for more equitable healthcare delivery.
  Medscape Medical News, November 16, 2023
• AHA 2023 More Evidence of Better Outcomes With 120 mm Hg BP Target Intensive lowering of blood pressure to a systolic target < 120 mm Hg reduced cardiovascular events among high-risk individuals by 12% vs a target < 140 mm Hg in the ESPRIT trial.
  Medscape Medical News, November 16, 2023
• AHA 2023 Pharmacist-Based Strategy Places More Patients on Statins In two studies run in parallel, testing different strategies, automatic referral to a pharmacist was superior to EHR alerts for increasing statin prescriptions for at-risk patients.
  MDedge News, November 16, 2023
• Cold-Water Swimming for Your Health? These Docs Say Jump In Evidence that cold-water plunges may have mental and physical health benefits continues to grow, and doctors and researchers who just plain love it are leading the charge.
  Medscape Medical News, November 15, 2023
• AAO 2023 At 2 Years, Anti-VEGF Treatment, Laser Equal for ROP: Study For treatment of retinopathy of prematurity, intravitreal aflibercept (Eylea) and laser photocoagulation showed equivocal results at age 2 years, a European-based clinical trial found.
  Medscape Medical News, November 15, 2023
• Blood Test for MS Activity Gets FDA Breakthrough Designation Roche's Elecsys NfL test is intended to be used as an aid in detection of disease activity in adults with relapsing-remitting multiple sclerosis or secondary progressive multiple sclerosis.
  Medscape Medical News, November 15, 2023
• Surveillance Imaging After Head, Neck Cancer Remission? With no apparent benefit for most, investigators say routine surveillance imaging in asymptomatic patients with head and neck cancer "should be discouraged."
  Medscape Medical News, November 15, 2023
• AHA 2023 Low-Salt Diet Cut BP by 6 mm Hg in 1 Week: CARDIA-SSBP The blood pressure reduction brought about by the low-sodium diet may be comparable to that produced by a single antihypertensive medication.
  Medscape Medical News, November 15, 2023
• AHA 2023 Dual Energy Conversion Safe, Reliable for AF With Obesity In patients with obesity, dual energy cardioversion is more reliable and just as safe as conventional single energy cardioversion as an initial strategy in AF, a new study shows.
  MDedge News, November 14, 2023