Diabetes & Endocrinology News

• KidneyWeek 2020 Novel Drug Slows Progression of Diabetic Kidney Disease Finerenone, a selective, nonsteroidal mineralocorticoid receptor antagonist, significantly reduced both renal and cardiovascular events, with good tolerability, in the FIDELIO-DKD trial.
  Medscape Medical News, October 23, 2020
• Hypothyroidism in Pregnant Woman May Raise Child's Risk of ADHD Low levels of maternal thyroid hormone during the first three months of pregnancy may influence a fetus's brain development leaving the child at a greater risk of ADHD, a new study suggests.
  Reuters Health Information, October 22, 2020
• Decision on Race Multiplier in CKD in Blacks 'Has Real Consequences' Dropping the eGFR multiplier for African Americans produced a 33% hike in those assigned to a more severe stage of chronic kidney disease. But whether or not to keep the adjustment remains unclear, say experts.
  Medscape Medical News, October 23, 2020
• Rates of Bone Density Testing in Men Initiating ADT Low but Rising While bone mineral density (BMD) testing is becoming more common among men initiating androgen deprivation therapy (ADT) for prostate cancer, a Canadian study suggests that most men still are not being assessed prior to treatment.
  Reuters Health Information, October 21, 2020
• Local Estrogen Therapy for Vaginal Atrophy Can Start Before or After Age 60 Treatment with low-dose local estrogen therapy (ET) to improve symptoms of vaginal atrophy may start before or after age 60, according to a post-hoc analysis of a randomized, placebo-controlled trial in the US and Canada.
  Reuters Health Information, October 21, 2020
• DVT Screening, Early Treatment, Prevent PE in Necrotizing Pancreatitis Ultrasound screening enabled identification and early treatment of extremity deep vein thrombosis (DVT), thereby preventing symptomatic pulmonary embolism (PE) in a single center trial.
  Reuters Health Information, October 21, 2020
• EAS 2020 Novel Dementia Risk Charts Underline the Role of Lifestyle The 'pessimistic' belief that an inherited risk for dementia means developing the disease is inevitable is belied by novel 10-year risk charts that emphasize the importance of lifestyle factors.
  Medscape Medical News, October 22, 2020
• Fertility Journal Editors Oppose Supreme Court Nominee Barrett's signature on a 2006 ad is stoking concerns about how attempts to outlaw abortion could potentially reduce access to IVF, leading a medical journal to oppose her Supreme Court nomination.
  Medscape Medical News, October 22, 2020
• ASRM 2020 Relugolix Combo Effective for Uterine Fibroids Through 1 Year An extension study of the LIBERTY 1 and 2 randomized controlled trials, LIBERTY 3, showed that the drug had efficacy through week 52, with no new safety signals.
  Medscape Medical News, October 22, 2020
• HIV Drugs Prevent Type 2 Diabetes, May Be Path to New Therapy An analysis of five databases shows that the NRTIs used to treat HIV and hepatitis B infection are able to prevent diabetes by blocking inflammasone activation; discovery may pave way for new therapeutics.
  Medscape Medical News, October 22, 2020
• 25 Drugs, Drug Classes Added to FDA's Safety Signal List The agency found a potential safety problem in a diabetes drug class. Several proton pump inhibitors and fibric acid derivatives also made the list.
  Medscape Medical News, October 21, 2020
• EASD 2020 'Modest' Benefit for Post-MI Flash Glucose Monitoring in T2D Following a heart attack, there appears to be a 'modest' benefit of using flash glucose monitoring over fingerstick testing in patients with type 2 diabetes being treated with insulin or a sulfonylurea.
  Medscape Medical News, October 21, 2020
• Glaring Gap Between Vit D Guidance and Practice in Care Homes Care home staff are not routinely giving residents Vitamin D supplements and wait for doctors to prescribe it, which rarely happens, public health experts find.
  Medscape Medical News, October 21, 2020
• TCT 2020 IN.PACT BTK: Step in the Right Direction for DCB in Below-Knee CLI The phase 2 study showed late lumen loss comparable to or better than angioplasty, with no safety signal in a space primed for new treatments.
  Medscape Medical News, October 20, 2020
• Trump, Tillis Weakness on Insulin Price Tags This election cycle — coinciding with a looming threat to the ACA and millions of people losing jobs and health insurance during the pandemic — the high price of prescription drugs has gained new meaning.
  Kaiser Health News, October 20, 2020
• Doctors Probe Whether COVID-19 Is Causing Diabetes Mario Buelna, a healthy 28-year-old father, caught a fever and started having trouble breathing in June. He soon tested positive for COVID-19.
  Reuters Health Information, October 19, 2020
• EASD 2020 Diabetic Neuropathic Pain Linked to Brain Bioenergic Anomalies Abnormal mitochondrial activity in the somatosensory cortex and right thalamus may explain why some patients with type 2 diabetes experience painful peripheral neuropathy, suggest findings of a UK study.
  Medscape Medical News, October 20, 2020
• US FDA Advises Against Dispensing Single Insulin Pens Notice clarifies prior label change stating packages containing five insulin pens should be dispensed intact in the original sealed carton.
  Medscape Medical News, October 20, 2020
• ASRM 2020 PCOS Tied to Risk for Cardiovascular Disease After Menopause Even controlling for other baseline risk factors for cardiovascular disease, women with PCOS were more like to have earlier cardiovascular events than women without PCOS.
  Medscape Medical News, October 19, 2020
• NAMS 2020 Genitourinary Syndrome of Menopause Statement Stresses Tx Options Providers should take a proactive approach to GSM and ask about symptoms as many women aren't aware that effective treatments are available.
  Medscape Medical News, October 19, 2020