Moderate to Severe Asthma: News

• EAACI 2021 Dupilumab Safe, Effective in Kids With Moderate-to-Severe Asthma Adding the dupilumab option for children in this age group is "huge," says one expert.
  Medscape Medical News, July 10, 2021
• ATS 2021 Tezepelumab Reduces Serious Exacerbations In Severe Asthma Results from the NAVIGATOR study showed that treatment of adults and adolescents with severe, uncontrolled asthma led to a large reduction in exacerbations requiring hospital stays and ED visits.
  Medscape Medical News, May 28, 2021
• PAS 2021 Nighttime Asthma Predicts Poor Outcomes in Teens Teens with persistent nocturnal asthma symptoms were significantly more likely than those without to report poor functional health independent of daytime asthma, based on data from 430 adolescents.
  Medscape Medical News, May 06, 2021
• Woman Recovering After Rare Windpipe Transplant From Donor Doctors say the drastic operation could potentially help other people left with serious windpipe damage from ventilators, including patients with COVID-19.
  Associated Press, April 06, 2021
• CDC Adds New Medical Conditions to COVID-19 High-Risk List Type 1 diabetes, liver disease, HIV, moderate asthma, overweight, and a number of neurologic conditions are now included, as some states proceed to open up vaccine availability to all adults.
  Medscape Medical News, March 31, 2021
• AAAAI 2021 Patients With Asthma Using Mepolizumab Had Fewer Exacerbations "Mepolizumab has clearly been shown to improve severe asthma control in many clinical trials, but atopy, obesity, and depression/anxiety affect patients with asthma at an increased rate."
  Medscape Medical News, March 03, 2021
• AAAAI 2021 Asthma Patients Say Most Doctors Don't Ask About Cannabis Use Among individuals with asthma and allergies who use cannabis, more than half said they aren't willing to discuss their use of cannabis with their doctor and their doctor doesn't ask.
  Medscape Medical News, March 02, 2021
• Asthma-COPD Overlap: Patients Have High Disease Burden Patients with asthma–chronic obstructive pulmonary disease overlap (ACO) experienced a higher burden of disease than patients with either asthma or COPD alone, a recent study has found.
  Medscape Medical News, January 15, 2021
• Landmark Ruling Links Death of UK Schoolgirl to Pollution Air pollution contributed to the death of a London schoolgirl, a coroner ruled on Wednesday in a landmark case that could push Britain to get tougher on traffic and clean up city air.
  Reuters Health Information, December 16, 2020
• Asthma Guidelines Update FeNO, Intermittent ICS Use The updated guidelines address six priority topics but notably exclude any recommendations for the use of fast-emerging biological therapy.
  Medscape Medical News, December 16, 2020
• CHEST 2020 No Evidence to Guide Selection of Biologic for Severe Asthma Many patients see a tremendous improvement in their severe asthma when they take a biologic, but there is no guidance to identify which biologic works best in which patient.
  Medscape Medical News, October 30, 2020
• ERS 2020 Oral Masitinib Phase 3 Results Promising for Severe Asthma The tyrosine kinase inhibitor reduced severe exacerbations by 35%, regardless of eosinophil count, in a population that hasn't had an effective oral treatment option, new research shows.
  Medscape Medical News, September 11, 2020
• ATS 2020 Oral Masitinib Improves Severe Asthma The small-molecule biologic reduces exacerbations in patients not responsive to steroids, new research shows.
  Medscape Medical News, May 28, 2020
• Asthma Patients Advised to Continue Therapy During Pandemic Two physicians cautioned colleagues that COVID-19 could be spawning hazardous behavior as patients question whether they should continue using immunosuppressive drugs during the pandemic.
  Medscape Medical News, May 16, 2020
• Alert EU Panel Backs Triple Combo Asthma Inhaler With Digital Sensor Enerzair Breezhaler combines indacaterol, glycopyrronium, and mometasone and comes with an optional digital sensor that collects data on patient use to support adherence.
  International Approvals, May 06, 2020
• AAAAI 2020 Asthma Patients: Stay on Steroids in Face of COVID-19, Say Experts Patients with asthma should stay on their preventive steroid therapy, both to protect against infection with COVID-19 as well as if they succumb to the virus, say experts in respiratory medicine.
  Medscape Medical News, March 20, 2020
• Alert FDA OKs Asthma Drug Benralizumab (Fasenra) for At-Home Use The Fasenra Pen is a prefilled, single-use autoinjector for use as adjunctive maintenance treatment for adults and for children aged 12 years or older who have severe eosinophilic asthma.
  FDA Approvals, October 04, 2019
• ERS 2019 One Inhaler Effective for Asthma Triple Therapy When a long-acting muscarinic antagonist is added to a single inhaler with a two-drug combination, lung function improves and asthma exacerbations decrease, according to new research.
  Medscape Medical News, October 01, 2019
• More Glucocorticoid, Not LABA, May Control Black Kids' Asthma Researchers report that some black children respond quite differently to treatment escalation than other racial/ethnic groups -- in a way that could change clinical practice.
  Medscape Medical News, September 27, 2019
• Alert FDA OKs Mepolizumab for Younger Children With Severe Asthma Nucala is the first biologic approved in the US for children aged 6 to 11 years with severe eosinophilic asthma.
  News Alerts, September 12, 2019