Moderate to Severe Asthma: News

• EAACI 2021 Tezepelumab Reduces Asthma Exacerbation Rates by 56% The biologic reduced the annualized exacerbation rate in a broad group of patients with severe asthma by 56% in the phase 3 NAVIGATOR trial.
  Medscape Medical News, July 14, 2021
• EAACI 2021 Short-Acting Beta Agonist Overuse 'a Global Public Health Issue' Overreliance on SABAs and underuse of inhaled corticosteroids are associated with increased risk of exacerbations and asthma-related death.
  Medscape Medical News, July 11, 2021
• EAACI 2021 Dupilumab Safe, Effective in Kids With Moderate-to-Severe Asthma Adding the dupilumab option for children in this age group is "huge," says one expert.
  Medscape Medical News, July 10, 2021
• ATS 2021 Tezepelumab Reduces Serious Exacerbations In Severe Asthma Results from the NAVIGATOR study showed that treatment of adults and adolescents with severe, uncontrolled asthma led to a large reduction in exacerbations requiring hospital stays and ED visits.
  Medscape Medical News, May 28, 2021
• PAS 2021 Nighttime Asthma Predicts Poor Outcomes in Teens Teens with persistent nocturnal asthma symptoms were significantly more likely than those without to report poor functional health independent of daytime asthma, based on data from 430 adolescents.
  Medscape Medical News, May 06, 2021
• Woman Recovering After Rare Windpipe Transplant From Donor Doctors say the drastic operation could potentially help other people left with serious windpipe damage from ventilators, including patients with COVID-19.
  Associated Press, April 06, 2021
• CDC Adds New Medical Conditions to COVID-19 High-Risk List Type 1 diabetes, liver disease, HIV, moderate asthma, overweight, and a number of neurologic conditions are now included, as some states proceed to open up vaccine availability to all adults.
  Medscape Medical News, March 31, 2021
• HRT Tied to Increased Risk of Severe Asthma Exacerbation Hormone replacement therapy may increase the risk of severe asthma exacerbations in peri- and post-menopausal asthmatic women, an observational study suggests.
  Reuters Health Information, March 26, 2021
• AAAAI 2021 Patients With Asthma Using Mepolizumab Had Fewer Exacerbations "Mepolizumab has clearly been shown to improve severe asthma control in many clinical trials, but atopy, obesity, and depression/anxiety affect patients with asthma at an increased rate."
  Medscape Medical News, March 03, 2021
• AAAAI 2021 Asthma Patients Say Most Doctors Don't Ask About Cannabis Use Among individuals with asthma and allergies who use cannabis, more than half said they aren't willing to discuss their use of cannabis with their doctor and their doctor doesn't ask.
  Medscape Medical News, March 02, 2021
• Bronchial Thermoplasty Benefits for Uncontrolled Asthma Sustained at 10 Years The benefits of bronchial thermoplasty in patients with uncontrolled asthma are sustained over at least 10 years, according to results of the BT10+ study.
  Reuters Health Information, February 19, 2021
• Benralizumab Improves Health-Related Quality of Life in Severe Eosinophilic Asthma Results of a phase 3b trial confirm and extend the efficacy of benralizumab for severe eosinophilic asthma, showing early and sustained improvements in patient-reported outcomes and quality of life.
  Reuters Health Information, January 15, 2021
• Asthma-COPD Overlap: Patients Have High Disease Burden Patients with asthma–chronic obstructive pulmonary disease overlap (ACO) experienced a higher burden of disease than patients with either asthma or COPD alone, a recent study has found.
  Medscape Medical News, January 15, 2021
• Disinfecting During Pandemic Puts Asthmatics at Risk Increased cleaning by people with asthma during the pandemic may be triggering flares of their disease, a new report suggests.
  Reuters Health Information, January 04, 2021
• Landmark Ruling Links Death of UK Schoolgirl to Pollution Air pollution contributed to the death of a London schoolgirl, a coroner ruled on Wednesday in a landmark case that could push Britain to get tougher on traffic and clean up city air.
  Reuters Health Information, December 16, 2020
• Asthma Guidelines Update FeNO, Intermittent ICS Use The updated guidelines address six priority topics but notably exclude any recommendations for the use of fast-emerging biological therapy.
  Medscape Medical News, December 16, 2020
• Oral Contraceptives May Curb Severe Asthma Attacks in Young Women Premenopausal women with asthma who use oral contraception that contains estrogen may be less likely to experience severe exacerbations, a new study suggests.
  Reuters Health Information, November 23, 2020
• Anti-IL-5 Biologics Effective for Up to 2 Years in Severe Asthma, but Residual Disease Remains More than 80% of patients with severe asthma responded to anti-IL-5 biologics in a 2-year follow-up study, but 69% experienced persistent airflow obstruction, uncontrolled asthma symptoms and other signs of residual disease.
  Reuters Health Information, October 29, 2020
• CHEST 2020 No Evidence to Guide Selection of Biologic for Severe Asthma Many patients see a tremendous improvement in their severe asthma when they take a biologic, but there is no guidance to identify which biologic works best in which patient.
  Medscape Medical News, October 30, 2020
• Extracorporeal CO2 Removal Effective in Status Asthmaticus Venovenous extracorporeal carbon dioxide removal (ECCO2R) may be lifesaving in patients with status asthmaticus refractory to maximal medical therapy, according to a retrospective review.
  Reuters Health Information, October 22, 2020