Center of Excellence: Cardiovascular Risk: News & Perspective

• Ultraprocessed Food Again Linked to Increased CVD, Death Individuals who consume a high proportion of ultraprocessed food in their diet were at a heightened risk for cardiovascular disease (CVD) and all-cause mortality, Italian researchers report.
  Medscape Medical News, December 24, 2020
• 6 Can't-Miss Guideline Changes for Primary Care   Dr Neil Skolnik briefly shares the most important guideline changes from 2020 that primary care providers need to know.
  Medscape Family Medicine, December 24, 2020
• ACC Issues Guidance on Antithrombotic Therapy The new document complements several disease treatment guidelines to provide guidance on antithrombotic use in patients with AF or VTE undergoing PCI or with ASCVD.
  Medscape Medical News, December 23, 2020
• Novartis Receives FDA Complete Response Letter on Inclisiran The FDA was unable to approve the new drug application for inclisiran, a novel treatment to lower LDL cholesterol, owing to unresolved facility inspection concerns, the company said.
  News Alerts, December 21, 2020
• EPA, DHA, and Inflammatory Markers: A Piece of the PUFA Puzzle? Why REDUCE-IT and JELIS, but not OMEMI, STRENGTH, ASCEND, or OMEGA? Why did CV risk fall in patients taking marine-oil-derived omega-3 polyunsaturated fatty acids in some trials but not others?
  Medscape Medical News, December 16, 2020
• Top Cardiology Trials of 2020 in Review   The annual tradition continues as did cardiology research despite a pandemic. Trials on fish oils, statins, SGLT2 inhibitors, and antiplatelets are among the selections of Drs Harrington and Gibson.
  theheart.org on Medscape, December 15, 2020
• LDL Not the Primary Culprit in ASCVD? LDL cholesterol has been seen as the main offender in ASCVD, but new studies implicate other lipids, including so-called "remnant" cholesterol. An editorial, however, urges caution in interpretation.
  Medscape Medical News, December 14, 2020
• GLP-1 Receptor Agonists at EASD 2020: Poster Pearls Dr Akshay Jain shares his top poster picks on GLP-1 receptor agonists from this year's EASD virtual meeting.
  Medscape Diabetes & Endocrinology, December 11, 2020
• Low Plasma Transthyretin Linked to Risk of Heart Failure Data from two prospective cohort studies of the Danish general population show that low plasma transthyretin concentrations were associated with a higher risk of incident heart failure.
  Medscape Medical News, December 10, 2020
• AHA 2020 Highlights: Investigational Drugs and Fish Oils   Top trials from the virtual AHA 2020 meeting featured a polypill and the novel drugs sotagliflozin, a dual SGLT 1 and -2 inhibitor, and omecamtiv mecarbil.
  theheart.org on Medscape, December 10, 2020
• Breast Cancer Survival Disparities: Need to Address Obesity Higher rates of obesity and comorbidities in Black women with early breast cancer may explain the differences in survival, and need to be addressed to improve outcomes.
  Medscape Medical News, December 10, 2020
• 'Suboptimal' Primary CVD Prevention for Sexual Minorities Cholesterol-lowering medications are indicated for primary prevention of cardiovascular disease, but are underprescribed in sexual minorities.
  Medscape Medical News, December 09, 2020
• Nighttime Airplane Noise Linked to Cardiovascular Death Noise pollution from airplanes may be as deleterious as air pollution in increasing risk for cardiac death.
  Medscape Medical News, December 08, 2020
• PFO Closure Beneficial in Stroke Patients With Thrombophilia Results from what is said to be the largest prospective study on recurrent events in hypercoagulable patients with PFO-associated embolism suggest that PFO closure is to be recommended in this group.
  Medscape Medical News, December 07, 2020
• Calcium Burden Drives CV Risk Whether CAD Is Obstructive or Not That future cardiovascular risk tracks closely with plaque burden, but not so much with whether the coronary disease is obstructive, may never have been so clearly illustrated.
  Medscape Medical News, December 07, 2020
• Peripheral Neuropathy Tied to Mortality in Adults Without Diabetes Decreased sensation in the foot may be associated with an increased risk of death, even among people with normoglycemia, a study indicates.
  Medscape Medical News, December 07, 2020
• New Residency Matching Sets Record, Says NRMP The highest number of applicants ever were matched to subspecialty training positions, as the number of US MD and international grads both increased.
  Medscape Medical News, December 04, 2020
• Colchicine a Case Study for What's Wrong With US Drug Pricing A Medicare/Medicaid analysis shows a prolonged public-spending burden, despite generics available outside the United States for pennies a pill. Meanwhile, use widens from gout to MI, even COVID-19.
  Medscape Medical News, December 02, 2020
• Air Pollution Linked to Brain Amyloid Pathology Higher levels of air pollution were associated with an increased risk for amyloid-beta pathology in a new study of older adults with cognitive impairment.
  Medscape Medical News, December 02, 2020
• New AHA Scientific Statement on Menopause and CVD Risk An AHA scientific statement aims to raise awareness of healthcare providers and women about the menopause transition as a time of increasing heart disease risk.
  Medscape Medical News, December 02, 2020