Center of Excellence: Cardiovascular Risk: News & Perspective

• Uric Acid Levels May Influence Mortality in OSA Data from NHANES showed a nonlinear association between serum uric acid levels and all-cause mortality and cardiovascular mortality.
  Medscape Medical News, November 28, 2023
• AHA 2023 AI Interpretation of CCTA: Inflammation as CV Risk Factor With the help of AI, arterial inflammation measured with coronary computed tomography angiography can predict fatal and nonfatal events in patients with nonobstructive CAD.
  MDedge News, November 27, 2023
• Bariatric Surgery Still Best Option for Some With Obesity Despite the rapid emergence of glucagonlike peptide-1 agonists for treating obesity, bariatric surgery may still be a better choice for some individuals, two experts say.
  Endocrine Society, November 27, 2023
• Not All Exercise Is Beneficial: The PA Paradox Explained Occupational, but not leisure-time, physical activity is linked to higher risks for dementia, cardiovascular disease, and mortality. Here's why.
  Medscape Medical News, November 27, 2023
• Long-Term Use of ADHD Meds and CVD Risk: New Data Despite previous mixed findings, results of a large Swedish study show an increased risk for CVD with long-term use of medications, especially stimulants, to treat attention-deficit/hyperactivity disorder.
  Medscape Medical News, November 22, 2023
• An Update on Lipoprotein(a): The Latest on Testing, Treatment, and Guideline Recommendations This review highlights the current state of Lipoprotein(a), including updates from clinical trial outcomes and guideline recommendations supporting once-in-a-lifetime measurement in most individuals with increased risk of atherosclerotic CVD.
  ACC.org, November 22, 2023
• AHA 2023 Promising First Results With DNA Editing to Lower LDL The first-in-human HEART-1 trial of in vivo DNA editing called VERVE-101, shows reductions in LDL and PCSK9 protein in patients with familial hypercholesterolemia.
  MDedge News, November 21, 2023
• Is Metabolically Healthy Obesity an 'Illusion'? Caroline Messer, MD, explains that helping patients with obesity lose weight will help them achieve true metabolic health.
  Medscape Diabetes & Endocrinology, November 21, 2023
• Placental Cell Disruption Tied to Adult Depression, CVD Disruption of placental Hofbauer cell function caused by prenatal infection or preterm birth may increase the risk for depression and cardiovascular disease in adulthood.
  Medscape Medical News, November 21, 2023
• PREVENT: AHA's New Risk Calculator Incorporates CKM Health The new cardiovascular disease risk equations start at age 30, include measures of kidney and metabolic health, add heart failure, and remove race from the equations.
  Medscape Medical News, November 20, 2023
• AHA 2023 Single Injection Reduces Blood Pressure for 6 Months The RNA interference therapeutic targeting synthesis of angiotensinogen lowered BP in adults with mild to moderate hypertension for up to 6 months after one dose in the phase 2 KARDIA-1 study.
  Medscape Medical News, November 20, 2023
• To Anticoagulate or Not in Subclinical AF   John Mandrola and ARTESiA investigator Jeff Healey discuss the results and how they compare with the NOAH-AFNET-6 data on the use of DOACs in patients with short-duration AF.
  theheart.org on Medscape, November 20, 2023
• Nov 17 2023 This Week in Cardiology  
  theheart.org on Medscape, November 17, 2023
• Kidney Week 2023 Albuminuria Reduction Fuels Finerenone's Kidney Benefits The findings of the mediation analyses underscore the important role that albuminuria plays in the nephropathy and related comorbidities associated with type 2 diabetes and CKD.
  MDedge News, November 17, 2023
• AASLD 2023 Novel Agent Seladelpar Improves Markers of PBC Activity For 1 in 4 patients with primary biliary cholangitis (PBC) who received the investigational PPAR-delta agonist, alkaline phosphatase levels normalized.
  Medscape Medical News, November 17, 2023
• A Better Way to Control Blood Pressure Follow the example of a primary care practice in Ohio that has successfully achieved > 90% blood pressure control in its patients with hypertension.
  Medscape Internal Medicine, November 17, 2023
• ACR 2023 Study Takes Fine-Grained Look at MACE Risk With GCs in RA 'Up to half of RA patients in the United States use long-term glucocorticoids despite previous work suggesting they increase MACE in a dose-dependent way.'
  MDedge News, November 16, 2023
• AHA 2023 More Evidence of Better Outcomes With 120 mm Hg BP Target Intensive lowering of blood pressure to a systolic target < 120 mm Hg reduced cardiovascular events among high-risk individuals by 12% vs a target < 140 mm Hg in the ESPRIT trial.
  Medscape Medical News, November 16, 2023
• Keeping It Simple: Treatment Choices for Atopic Dermatitis   Experts discuss effective nonsteroidal and alternative topicals for mild atopic dermatitis and the expanding range of systemic therapies, including JAK inhibitors, for patients with severe AD.
  Medscape, November 16, 2023
• Sleeping Beats Sitting? What a New Study Means for Your Patients Mounting evidence suggests that even small movement changes can benefit cardiometabolic health.
  Medscape Medical News, November 15, 2023
• Even an Hour's Walk a Week Lowers Risk in Type 2 Diabetes Leisure time activity equivalent to less than 1.5 hours' walking time per week may be enough to substantially reduce the risk for neuropathy and nephropathy in type 2 diabetes, say Danish researchers.
  Medscape Medical News, August 29, 2023
• Artificial Sweeteners Increase Cardiovascular Risk A recent scientific review confirms that artificial sweeteners affect primary cardiovascular risk factors.
  Medscape Medical News, August 22, 2023
• Firefighters Fight Fat With Mediterranean Diet Adoption A communal approach to adopting the Mediterranean diet lowered firefighters' risks for cardiovascular disease and cancer and improved their dietary adherence, both at home and work.
  Medscape Medical News, August 18, 2023
• Rheumatoid Arthritis May Raise Risk for Aortic Stenosis Data from a large cohort study also showed an increase in risk for aortic stenosis–related interventions and death.
  Medscape Medical News, July 31, 2023
• Cardiovascular Risk Linked with Severe COVID Risk People with an elevated 10-year cardiovascular risk score are linked to more severe COVID outcomes, in a new study.
  Medscape News UK, April 14, 2022
• Call for Tighter LDL Targets for Highest Risk Patients With multiple new lipid-lowering drugs coming on the market, and European guidelines suggesting lower than ever targets in patients with very high cardiovascular risk, experts say aim for ‘ones not twos’ with low-density lipoprotein (LDL) targets.
  Medscape News UK, November 15, 2021